7-chlorokynurenic acid

 
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
Central nervous system myelin is a specialized structure produced by oligodendrocytes that ensheaths axons, allowing rapid and… (More)
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Highly Cited
2006
Highly Cited
2006
Ischemic depolarizing events, such as repetitive spontaneous periinfarct spreading depolarizations (PIDs), expand the infarct… (More)
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2003
2003
Rationale. Histamine plays an important role in modulating acquisition and retention in learning and memory process in… (More)
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2000
2000
7-Chlorokynurenic acid 1 is a potent glycine-N-methyl-D-aspartate (NMDA) receptor antagonist, but it shows weak activity after… (More)
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2000
2000
We have synthesized D-glucose or D-galactose esters of 7-chlorokynurenic acid (7ClKynA) as prodrugs to facilitate the transport… (More)
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1996
1996
7-Chlorokynurenic acid (7-Cl-KYNA) and 5,7-dichlorokynurenic acid (5,7-Cl2-KYNA) are of therapeutic interest as potent glycine/N… (More)
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Highly Cited
1996
Highly Cited
1996
The N-methyl-D-aspartate (NMDA) subtype of ionotropic glutamate receptors is a heterooligomeric membrane protein composed of… (More)
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Highly Cited
1994
Highly Cited
1994
Activation of the NMDA subtype of ionotropic glutamate receptors requires binding of both L-glutamate and the coagonist glycine… (More)
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Highly Cited
1990
Highly Cited
1990
1. Responses to N-methyl-D-aspartic acid (NMDA) were recorded from mouse embryonic hippocampal neurones in dissociated culture… (More)
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Highly Cited
1988
Highly Cited
1988
Glycine markedly potentiates N-methyl-D-aspartate (N-Me-D-Asp) responses in mammalian neurons by an action at a modulatory site… (More)
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