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7-bromoindirubin-3'-oxime

Known as: 7BIO cpd 
National Institutes of Health

Papers overview

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2017
2017
Indirubins are natural occurring alkaloids extracted from indigo dye-containing plants. Indirubins could inhibit various kinases… 
2015
2015
BackgroundThe indirubin derivative 7-bromoindirubin-3′-oxime (7BIO) has already shown anticancer properties by causing cell death… 
2015
2015
2009
2009
The bis-indole alkaloid indirubin and its analogues bear a very interesting natural pharmacophore. They are recognized mainly as… 
Highly Cited
2009
Highly Cited
2009
Cells undergoing necrosis release endogenous danger signals that possess proinflammatory potential. In this study we show that… 
Highly Cited
2007
Highly Cited
2007
A variation of the bromine substitution from 6- to 7-position converts the glycogen synthase kinase-3alpha/beta-(GSK-3-alpha/beta… 
Highly Cited
2006
Highly Cited
2006
Indirubin, an isomer of indigo, is a reported inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3…