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7-bromoindirubin-3'-oxime
Known as:
7BIO cpd
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Indoles
Oximes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Modulation of glioma-inflammation crosstalk profiles in human glioblastoma cells by indirubin-3'-(2,3 dihydroxypropyl)-oximether (E804) and 7-bromoindirubin-3'-oxime (7BIO).
M. Scobie
,
Haley Houke
,
C. Rice
Chemico-biological interactions
2019
Corpus ID: 202555424
2017
2017
Indirubin Derivative 7-Bromoindirubin-3-Oxime (7Bio) Attenuates Aβ Oligomer-Induced Cognitive Impairments in Mice
Li-ping Chen
,
Chunhui Huang
,
+8 authors
W. Cui
Front. Mol. Neurosci.
2017
Corpus ID: 296134
Indirubins are natural occurring alkaloids extracted from indigo dye-containing plants. Indirubins could inhibit various kinases…
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2015
2015
Induction of atypical cell death in thyroid carcinoma cells by the indirubin derivative 7-bromoindirubin-3′-oxime (7BIO)
M. Broecker-Preuss
,
N. Becher-Boveleth
,
S. Gall
,
Katrin Rehmann
,
Susann Schenke
,
K. Mann
Cancer Cell International
2015
Corpus ID: 15553510
BackgroundThe indirubin derivative 7-bromoindirubin-3′-oxime (7BIO) has already shown anticancer properties by causing cell death…
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2015
2015
An evaluation of indirubin analogues as phosphorylase kinase inhibitors.
Jaida Begum
,
V. Skamnaki
,
+6 authors
J. Hayes
Journal of molecular graphics & modelling
2015
Corpus ID: 978193
2012
2012
Induction of discrete apoptotic pathways by bromo-substituted indirubin derivatives in invasive breast cancer cells.
K. Nicolaou
,
Vasilis Liapis
,
+6 authors
A. Constantinou
Biochemical and biophysical research…
2012
Corpus ID: 9739418
2009
2009
Synthesis and antiproliferative activity of 7-azaindirubin-3'-oxime, a 7-aza isostere of the natural indirubin pharmacophore.
M. Kritsanida
,
P. Magiatis
,
A. Skaltsounis
,
Youyi Peng
,
P. Li
,
L. Wennogle
Journal of natural products
2009
Corpus ID: 11172585
The bis-indole alkaloid indirubin and its analogues bear a very interesting natural pharmacophore. They are recognized mainly as…
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Highly Cited
2009
Highly Cited
2009
Cutting Edge: Necrosis Activates the NLRP3 Inflammasome1
Hanfen Li
,
A. Ambade
,
F. Re
The Journal of Immunology
2009
Corpus ID: 5125197
Cells undergoing necrosis release endogenous danger signals that possess proinflammatory potential. In this study we show that…
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2008
2008
7-Bromoindirubin-3'-oxime uncovers a serine protease-mediated paradigm of necrotic cell death.
J. Ribas
,
V. Yuste
,
X. Garrofé-Ochoa
,
L. Meijer
,
J. Esquerda
,
J. Boix
Biochemical pharmacology
2008
Corpus ID: 24832715
Highly Cited
2007
Highly Cited
2007
An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins.
V. Myrianthopoulos
,
P. Magiatis
,
Y. Ferandin
,
A. Skaltsounis
,
L. Meijer
,
E. Mikros
Journal of medicinal chemistry
2007
Corpus ID: 24184048
A variation of the bromine substitution from 6- to 7-position converts the glycogen synthase kinase-3alpha/beta-(GSK-3-alpha/beta…
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Highly Cited
2006
Highly Cited
2006
7-Bromoindirubin-3′-oxime induces caspase-independent cell death
J. Ribas
,
K. Bettayeb
,
+10 authors
L. Meijer
Oncogene
2006
Corpus ID: 25032035
Indirubin, an isomer of indigo, is a reported inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3…
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