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6-thioguanosine

Known as: 2-amino-9-beta-D-ribofuranosyl-9H-purine-6-thiol, 6-mercaptoguanosine 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Patients treated with the immunosuppressant and anticancer drugs 6-thioguanine, azathioprine, or mercaptopurine can metabolize… Expand
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Highly Cited
2010
Highly Cited
2010
RNA transcripts are subjected to post-transcriptional gene regulation by interacting with hundreds of RNA-binding proteins (RBPs… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS Azathioprine is the gold standard for immunosuppressive therapy in Crohn's disease (CD) and its molecular… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Measurement of 6-thioguanine nucleotide (6-TGN) concentrations in erythrocytes is widely accepted for use in… Expand
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Highly Cited
1991
Highly Cited
1991
The levels of several RNA transcripts in cultured hepatocytes are regulated by transcriptional and post-transcriptional… Expand
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Highly Cited
1990
Highly Cited
1990
Novel analogues of the naturally occurring purine nucleosides were synthesized in the thiazolo[4,5-d]pyrimidine ring system to… Expand
Highly Cited
1984
Highly Cited
1984
Abstract: The transport of [3H]deoxyuridine by the active nucleoside transport system into the isolated rabbit choroid plexus was… Expand
Highly Cited
1978
Highly Cited
1978
Isolation of newly synthesised RNA can be achieved by treatment of cells in culture with 6-thioguanosine or 4-thiouridine… Expand
Highly Cited
1975
Highly Cited
1975
The effects of 6-thioguanine on purine biosynthesis and cell viability have been examined in H.Ep. 2 cells grown in culture… Expand
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Highly Cited
1975
Highly Cited
1975
Abstract Adenosine deaminase (adenosine aminohydrolase, EC 3.5.4.4) has been purified about 3000-fold from human erythrocytes… Expand