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To study the chemical constituents of the roots of Chloranthus henryi.
The constituents of Chloranthus henryi were… Expand This paper reports the synthesis of 4-methoxymethyl and 4-acetoxymethyl-6,9-dimethyl-2H-thieno[3,2-g]-1-benzopyran-2-one as well… Expand To determine whether the activity of cytochrome P450 isoforms involved in the metabolism of (R) ‐warfarin is enhanced in cystic… Expand We used adult rat hepatocytes in primary culture (HPC) as a model system to study the hepatic phase II metabolism of the… Expand Healthy men were administered i.v. racemic warfarin, S-warfarin or R-warfarin on two occasions, once in the drug-free state and… Expand Abstract The hepatic microsomal metabolism of R and S warfarin, supported by NADPH or cumene hydroperoxide, has been investigated… Expand Abstract The chlorinated insecticides, mirex and Kepone, pose a threat to human health as a consequence of their pollution of the… Expand An examination of the metabolic fate of the R and the S isomers of warfarin revealed that the two isomers were metabolized by… Expand Warfarin and its metabolites were excreted by the rat in urine (two-thirds of the dose) and feces (one-third of the dose). For… Expand Abstract The metabolism of warfarin to 6-, 7- and 8-hydroxywarfarin occurs in rat liver microsomes and requires NADPH and… Expand