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6-hydroxywarfarin

Known as: 4,6-dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1- benzopyran-2-one 
National Institutes of Health

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Broader (1)

Warfarin
analogs & derivatives

Papers overview

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2005
2005
[Studies on the chemical constituents from the roots of Chloranthus henryi].
AIM To study the chemical constituents of the roots of Chloranthus henryi. METHODS The constituents of Chloranthus henryi were… 
2004
2004
Coumarin glycosides ofHaplophyllum performatum. structures of haploperosides C, D, and E
New coumarin glycosides — haploperosides C, D, and E — have been isolated from the epigeal part of theHaplophyllum performatum… 
1997
1997
Conversion of 7-methoxy-3,4-dihydro-2H-1-benzopyran-2-one into the corresponding dimethyl ortho ester
1994
1994
Disposition of drugs in cystic fibrosis. VI. In vivo activity of cytochrome P450 isoforms involved in the metabolism of (R)‐warfarin (including P450 3A4) is not enhanced in cystic fibrosis
To determine whether the activity of cytochrome P450 isoforms involved in the metabolism of (R) ‐warfarin is enhanced in cystic… 
1993
1993
Disposition of drugs in cystic fibrosis. V. In vivo CYP2C9 activity as probed by (S)‐warfarin is not enhanced in cystic fibrosis
Enhanced metabolism of theophylline in subjects with cystic fibrosis suggests that the activity of certain cytochrome P450… 
1993
1993
Warfarin metabolites: stereochemical aspects of protein binding and displacement by phenylbutazone.
The in vitro human serum albumin binding characteristics of the enantiomers of the major metabolites of warfarin [6… 
1992
1992
Phase II metabolism of warfarin in primary culture of adult rat hepatocytes.
We used adult rat hepatocytes in primary culture (HPC) as a model system to study the hepatic phase II metabolism of the… 
1991
1991
Selective inhibition of warfarin metabolism by diltiazem in humans.
Healthy men were administered i.v. racemic warfarin, S-warfarin or R-warfarin on two occasions, once in the drug-free state and… 
1979
1979
Cumene hydroperoxide-supported microsomal hydroxylations of warfarin--a probe of cytochrome P-450 multiplicity and specificity.
Highly Cited
1970
Highly Cited
1970
The metabolism of 4-C14-warfarin sodium by the rat.
Warfarin and its metabolites were excreted by the rat in urine (two-thirds of the dose) and feces (one-third of the dose). For… 
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