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6-hydroxywarfarin

Known as: 4,6-dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1- benzopyran-2-one 
National Institutes of Health

Papers overview

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2005
2005
AIM To study the chemical constituents of the roots of Chloranthus henryi. METHODS The constituents of Chloranthus henryi were… Expand
1998
1998
This paper reports the synthesis of 4-methoxymethyl and 4-acetoxymethyl-6,9-dimethyl-2H-thieno[3,2-g]-1-benzopyran-2-one as well… Expand
1994
1994
To determine whether the activity of cytochrome P450 isoforms involved in the metabolism of (R) ‐warfarin is enhanced in cystic… Expand
1992
1992
We used adult rat hepatocytes in primary culture (HPC) as a model system to study the hepatic phase II metabolism of the… Expand
1991
1991
Healthy men were administered i.v. racemic warfarin, S-warfarin or R-warfarin on two occasions, once in the drug-free state and… Expand
1979
1979
Abstract The hepatic microsomal metabolism of R and S warfarin, supported by NADPH or cumene hydroperoxide, has been investigated… Expand
Highly Cited
1978
Highly Cited
1978
Abstract The chlorinated insecticides, mirex and Kepone, pose a threat to human health as a consequence of their pollution of the… Expand
Highly Cited
1974
Highly Cited
1974
An examination of the metabolic fate of the R and the S isomers of warfarin revealed that the two isomers were metabolized by… Expand
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Highly Cited
1970
Highly Cited
1970
Warfarin and its metabolites were excreted by the rat in urine (two-thirds of the dose) and feces (one-third of the dose). For… Expand
1968
1968
Abstract The metabolism of warfarin to 6-, 7- and 8-hydroxywarfarin occurs in rat liver microsomes and requires NADPH and… Expand