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6-benzyl-1-benzyloxymethyl-5-iodouracil

 
National Institutes of Health

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2 relations

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Uracil
analogs & derivatives

Papers overview

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2018
2018
Effects of crystalline state and self-nanoemulsifying drug delivery system (SNEDDS) on oral bioavailability of the novel anti-HIV compound 6-benzyl-1-benzyloxymethyl-5-iodouracil in rats.
The objective of this study was to investigate the effect of crystalline state and a formulation of self-nanoemulsifying drug… Expand
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2017
2017
Identification of cytochrome P450s involved in the metabolism of 6-benzyl-1-benzyloxymethyl-5-iodouracil (W-1) using human recombinant enzymes and rat liver microsomes in vitro.
1. The aim of this study was to identify the hepatic metabolic enzymes, which involved in the biotransformation of 6-benzyl-1… Expand
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2016
2016
Profile of disposition, tissue distribution and excretion of the novel anti-human immunodeficiency virus (HIV) agent W-1 in rats
The purpose of this study was to characterize the disposition, distribution, excretion and plasma protein binding of 6-benzyl-1… Expand
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2015
2015
Development and validation of a high performance liquid chromatography method for determination of 6-benzyl-1-benzyloxymethyl-5-iodouracil (W-1), a novel non-nucleoside reverse transcriptase…
A sensitive and selective high-performance liquid chromatographic (HPLC) method for determination of 6-benzyl-1-benzyloxymethyl-5… Expand
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