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5-methyltetrahydrofolic acid

Known as: N(5)-methyltetrahydrofolic acid 
National Institutes of Health

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5-methyltetrahydrofolate

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Review
2007
Review
2007
Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK.
Following an introduction of the importance of folates and the rationale for seeking to estimate fractional folate absorption… Expand
Highly Cited
2004
Highly Cited
2004
5-Methyltetrahydrofolic acid and folic acid measured in plasma with liquid chromatography tandem mass spectrometry: applications to folate absorption and metabolism.
We describe a liquid chromatography (LC) tandem mass spectrometry (MS-MS) method for the determination of 5-methyltetrahydrofolic… Expand
Highly Cited
2003
Highly Cited
2003
Model studies on the stability of folic acid and 5-methyltetrahydrofolic acid degradation during thermal treatment in combination with high hydrostatic pressure.
Stability of folic acid and 5-methyltetrahydrofolic acid in phosphate buffer (0.2 M; pH 7) toward thermal (above 65 degrees C… Expand
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Highly Cited
1993
Highly Cited
1993
Oral 5′-methyltetrahydrofolic acid in senile organic mental disorders with depression: Results of a double-blind multicenter study
Abstract5′-Methyltetrahydrofolic acid (5′- MTHF) in addition to standard psychotropic medication significantly improved clinical… Expand
Highly Cited
1992
Highly Cited
1992
Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.
In some epithelial cells studied in vitro a membrane-bound folate receptor initiates the process for cell accumulation of 5… Expand
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Highly Cited
1990
Highly Cited
1990
The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway
The folate receptor, also known as the membrane folate-binding protein, is maximally expressed on the surface of folate-depleted… Expand
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Highly Cited
1978
Highly Cited
1978
Transport of 5-methyltetrahydrofolic acid and folic acid in freshly isolated hepatocytes.
Transport of 5-methyltetrahydropteroylglutamic acid (5CH,-H,PteGlu) was studied in hepatocytes isolated from rat liver by… Expand
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Highly Cited
1975
Highly Cited
1975
5-methyltetrahydrofolic acid is not a methyl donor for biogenic amines: enzymatic formation of formaldehyde.
Contrary to previous reports, 5-methyltetrahydrofolic acid does not mediate the methylation of dopamine to epinine. Instead, this… Expand
Highly Cited
1975
Highly Cited
1975
ENZYMATIC FORMATION OF TETRAHYDRO‐β‐CARBOLINE FROM TRYPTAMINE AND 5‐METHYLTETRAHYDROFOLIC ACID IN RAT BRAIN FRACTIONS: REGIONAL AND SUBCELLULAR DISTRIBUTION
—In rat brain extract tryptamine is converted to 1,2,3,4‐tetrahydro‐β‐carboline (THβJC) and N‐methyltryptamine to 2‐methyl‐THβC… Expand
Highly Cited
1974
Highly Cited
1974
5-Methyltetrahydrofolic Acid as a Mediator in the Formation of Pyridoindoles
Enzymes from chick and rat tissues catalyze the reaction of N-methyl tryptamine with 5-methyltetrahydrofolic acid to form 2,3,4,9… Expand
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