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5-methyltetrahydrofolic acid

Known as: N(5)-methyltetrahydrofolic acid 
 
National Institutes of Health

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5-methyltetrahydrofolate

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Review
2007
Review
2007
Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK.
Following an introduction of the importance of folates and the rationale for seeking to estimate fractional folate absorption… Expand
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Highly Cited
2005
Highly Cited
2005
Water-soluble vitamins.
Simultaneous Determination of Vitamins.--Klejdus et al. described a simultaneous determination of 10 water- and 10 fat-soluble… Expand
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Highly Cited
2004
Highly Cited
2004
5-Methyltetrahydrofolic acid and folic acid measured in plasma with liquid chromatography tandem mass spectrometry: applications to folate absorption and metabolism.
We describe a liquid chromatography (LC) tandem mass spectrometry (MS-MS) method for the determination of 5-methyltetrahydrofolic… Expand
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Highly Cited
2004
Highly Cited
2004
Determination of folate vitamers in human serum by stable-isotope-dilution tandem mass spectrometry and comparison with radioassay and microbiologic assay.
BACKGROUND Current clinical methods for folate give different results and cannot measure the various forms of folate. We… Expand
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Highly Cited
2004
Highly Cited
2004
Comparative study on pressure and temperature stability of 5-methyltetrahydrofolic acid in model systems and in food products.
A comparative study on the pressure and temperature stability of 5-methyltetrahydrofolic acid (5-CH(3)-H(4)folate) was performed… Expand
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2003
2003
Model studies on the stability of folic acid and 5-methyltetrahydrofolic acid degradation during thermal treatment in combination with high hydrostatic pressure.
Stability of folic acid and 5-methyltetrahydrofolic acid in phosphate buffer (0.2 M; pH 7) toward thermal (above 65 degrees C… Expand
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Highly Cited
1998
Highly Cited
1998
Role of folate receptor and reduced folate carrier in the transport of 5-methyltetrahydrofolic acid in human ovarian carcinoma cells.
Folate receptor-alpha (FR-alpha) is generally over-expressed in non-mucinous human ovarian carcinomas. The meaning of FR-alpha… Expand
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Highly Cited
1993
Highly Cited
1993
Oral 5′-methyltetrahydrofolic acid in senile organic mental disorders with depression: Results of a double-blind multicenter study
Abstract5′-Methyltetrahydrofolic acid (5′- MTHF) in addition to standard psychotropic medication significantly improved clinical… Expand
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Highly Cited
1992
Highly Cited
1992
Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.
In some epithelial cells studied in vitro a membrane-bound folate receptor initiates the process for cell accumulation of 5… Expand
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Highly Cited
1990
Highly Cited
1990
The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway
The folate receptor, also known as the membrane folate-binding protein, is maximally expressed on the surface of folate-depleted… Expand
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