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5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha

Known as: AMPK Alpha, PRKAA, AMPK Subunit Alpha 
A family comprised of two proteins that can each act as the catalytic alpha subunit for the 5'-AMP-activated protein kinase (AMPK) complex. The AMPK… 
National Institutes of Health

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6 relations
AMP-Activated Protein KinasesNUAK1 protein, humanPhosphorylationPhosphotransferases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK.
Reactive oxygen species (ROS) and nitric oxide (NO) have been implicated in the regulation of skeletal muscle glucose uptake… 
Highly Cited
2009
Highly Cited
2009
Curcumin disrupts the Mammalian target of rapamycin-raptor complex.
Curcumin (diferuloylmethane), a polyphenol natural product of the plant Curcuma longa, is undergoing early clinical trials as a… 
Highly Cited
2009
Highly Cited
2009
Catechin-induced activation of the LKB1/AMP-activated protein kinase pathway.
Highly Cited
2009
Highly Cited
2009
Stretch‐stimulated glucose uptake in skeletal muscle is mediated by reactive oxygen species and p38 MAP‐kinase
Alternatives to the canonical insulin‐stimulated pathway for glucose uptake are exercise‐ and exogenous reactive oxygen species… 
Highly Cited
2008
Highly Cited
2008
Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats.
Exercise training is commonly prescribed for treatment of nonalcoholic fatty liver disease (NAFLD). We sought to determine… 
Highly Cited
2007
Highly Cited
2007
Leucine stimulates mammalian target of rapamycin signaling in C2C12 myoblasts in part through inhibition of adenosine monophosphate-activated protein kinase.
Mammalian target of rapamycin (mTOR) signaling is one of the main signaling pathways controlling protein synthesis. Leucine… 
Highly Cited
2006
Highly Cited
2006
Activation of cardiac AMP-activated protein kinase by LKB1 expression or chemical hypoxia is blunted by increased Akt activity.
AMP-activated protein kinase (AMPK) plays a major role in the regulation of cardiac energy substrate utilization and can be… 
Highly Cited
2006
Highly Cited
2006
Rosiglitazone suppresses human lung carcinoma cell growth through PPARgamma-dependent and PPARgamma-independent signal pathways.
Peroxisome proliferator-activated receptors gamma (PPARgamma) exert diverse effects on cancer cells. Recent studies showed that… 
Highly Cited
2005
Highly Cited
2005
Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics.
Adiponectin is an adipocyte-derived hormone associated with antidiabetic actions. In rodent skeletal muscle, globular adiponectin… 
Highly Cited
2004
Highly Cited
2004
AMP-activated Protein Kinase Is Required for the Lipid-lowering Effect of Metformin in Insulin-resistant Human HepG2 Cells*
The antidiabetic drug metformin stimulates AMP-activated protein kinase (AMPK) activity in the liver and in skeletal muscle. To… 
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