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4-phenylpiperidine

National Institutes of Health

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Piperidines

Papers overview

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2015
2015
Kappa Antagonist JDTic in Phase 1 Clinical Trial
The biological bases for depression are unknown, but it is clear that depressive episodes can be precipitated by stressful… 
Highly Cited
2006
Highly Cited
2006
Synthesis and binding affinities of methylvesamicol analogs for the acetylcholine transporter and sigma receptor.
2005
2005
In vitro characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino]cyclohexanol [(+)-pIV] as a sigma-1 receptor ligand.
2000
2000
Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype.
Antagonists at the 1A/2B subtype of the NMDA receptor (NR1A/2B) are typically small molecules that consist of a 4-benzyl- or a 4… 
1997
1997
Tramadol withdrawal in a neonate
1995
1995
Synthesis of radioiodinated analogs of 2-(4-phenylpiperidino)cyclohexanol (vesamicol) as vesamicol-like agent.
1995
1995
In vivo characterization of radioiodinated 2-(4-phenylpiperidino)cyclohexanol (vesamicol) analogs: potential radioligand for mapping presynaptic cholinergic neurons.
1991
1991
Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands.
sigma receptors may represent an exciting new approach for the development of novel psychotherapeutic agents. Unfortunately, many… 
Highly Cited
1987
Highly Cited
1987
Structural determinants of sigma receptor affinity.
The structural determinants of sigma receptor affinity have been evaluated by examining a wide range of compounds related to… 
1982
1982
Conformation-activity study of 4-phenylpiperidine analgesics.
A conformational study of various 4-phenylpiperidine analgesics (the prodines, ketobemidone, meperidine, and 1,3,4-trimethyl-4… 
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