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4-oxoretinoic acid

Known as: 4-ketoretinoic acid 
National Institutes of Health

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2 relations

Broader (1)

Tretinoin
analogs & derivatives

Papers overview

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2015
2015
LRAT Overexpression Diminishes Intracellular Levels of Biologically Active Retinoids and Reduces Retinoid Antitumor Efficacy in the Murine Melanoma B16F10 Cell Line
Background/Aim: Vitamin A (all-trans-retinol, ATRol) serves as a precursor for all-trans-retinoic acid (ATRA), a ligand for the… 
2003
2003
Homozygous deletion of the CRABPI gene in AB1 embryonic stem cells results in increased CRABPII gene expression and decreased intracellular retinoic acid concentration.
1999
1999
Analysis of cyclic and acyclic analogs of retinol, retinoic acid, and retinal by laser desorption ionization-, matrix-assisted laser desorption ionization-mass spectrometry, and UV/Vis spectroscopy.
Laser desorption ionization (LDI)- and matrix-assisted laser desorption ionization (MALDI)-mass spectrometry (LDI-MS, MALDI-MS… 
1997
1997
Reduction of serum retinol levels following a single oral dose of all-trans retinoic acid in humans.
Following a single oral dose of all-trans retinoic acid (RA) (0.167 mmole) in corn oil to 6 healthy human subjects, the mean… 
Highly Cited
1995
Highly Cited
1995
Efficacy of all-trans-beta-carotene, canthaxanthin, and all-trans-, 9-cis-, and 4-oxoretinoic acids in inducing differentiation of an F9 embryonal carcinoma RAR beta-lacZ reporter cell line.
A reporter cell line was established from F9 mouse teratocarcinoma cells containing the RAR beta 2 promoter coupled to the lacZ… 
1994
1994
Cancer chemopreventive 3-substituted-4-oxoretinoic acids.
The introduction of substituents at position 3 of methyl 4-oxoretinoate can be effected in good yields by alkylating the lithium… 
Review
1989
Review
1989
Synthesis and evaluation of some new retinoids for cancer chemoprevention.
1988
1988
Increased retinoic acid metabolism following 3,3',4,4',5,5'-hexabromobiphenyl injection.
Young male Wistar rats received single i.p. injections of 3,3',4,4',5,5'-hexabromobiphenyl. In rats dosed with 40 mg/kg, food… 
1988
1988
Purification and properties of cellular retinoic acid-binding protein from neonatal rat skin.
Highly Cited
1979
Highly Cited
1979
Isolation and identification of 4-hydroxy- and 4-oxoretinoic acid. In vitro metabolites of all-trans-retinoic acid in hamster trachea and liver.
Incubation of [3H]retinoic acid in the presence of hamster liver 10000g supernatant produces several metabolites that are more… 
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