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4-hydroxyestrone

Known as: 4-OHE1, 4-OHE(1), 3,4-Dihydroxyestra-1,3,5(10)-trien-17-one 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 4 by cytochrome P450 (CYP… 
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
We systematically characterized the oxidative metabolites of 17beta-estradiol and estrone formed by 15 human cytochrome P450 (CYP… 
Review
2002
Highly Cited
2001
Highly Cited
2001
The oxidative metabolism of 17beta-estradiol (E2) and estrone (E1) to catechol estrogens (2-OHE2, 4-OHE2, 2-OHE1, and 4-OHE1) and… 
Review
2000
Review
2000
Estrogens induce tumors in laboratory animals and have been associated with breast and uterine cancers in humans. In relation to… 
Highly Cited
1999
Highly Cited
1999
Considering the physiologic importance of the steroid response, which is regulated in part by steroid levels in a given tissue… 
Highly Cited
1998
Highly Cited
1998
Catechol estrogen quinones (CE-Q) have been implicated as ultimate carcinogenic metabolites in estrogen-induced carcinogenesis… 
Highly Cited
1994
Highly Cited
1994
Review
1993
Review
1993