4-hydroxyantipyrine

Study Objective. To evaluate the metabolism of antipyrine, a general metabolic probe, caffeine, a probe for cytochrome P450 (CYP… Expand

Antipyrine has been widely used as a probe drug for human oxidative drug metabolism. To evaluate the role of antipyrine as a… Expand

The elimination of diazepam and antipyrine and the urinary excretion of their metabolites were investigated in 21 healthy… Expand

The effect of liver cirrhosis on plasma clearance and metabolite profile of i.v. administered antipyrine was studied in 23… Expand

A rapid, selective and sensitive method was developed for the determination of antipyrine and its main metabolites in plasma… Expand

1 The influence of enzyme induction with antipyrine and pentobarbitone was studied on the rates of formation of the major… Expand

Adult, male, unmedicated twins received antipyrine orally under carefully controlled environmental conditions. Relative… Expand

1. The amounts of antipyrine and its metabolites excreted in 24 h urine after i.v. injection of 10 mg antipyrine into male Wistar… Expand

Summary Twelve common drugs that are tertiary amines react with nitrite in aqueous solution at ph 3 to 4 to form… Expand

In the previous paper, it was shown that antipyrine was oxidized not only to 4-hydroxyantipyrine, but also to 3-hydroxymethyl-2… Expand