4-hydroxyantipyrine
National Institutes of Health
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Study Objective. To evaluate the metabolism of antipyrine, a general metabolic probe, caffeine, a probe for cytochrome P450 (CYP…
1. Three model substrates for the characterization of drug oxidation activity, antipyrine (AP), hexobarbitone (HB) and…
1 The influence of enzyme induction with antipyrine and pentobarbitone was studied on the rates of formation of the major…
Adult, male, unmedicated twins received antipyrine orally under carefully controlled environmental conditions. Relative…
In the previous paper, it was shown that antipyrine was oxidized not only to 4-hydroxyantipyrine, but also to 3-hydroxymethyl-2…