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4-hydroxyantipyrine

 
National Institutes of Health

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Highly Cited
2000
Highly Cited
2000
Study Objective. To evaluate the metabolism of antipyrine, a general metabolic probe, caffeine, a probe for cytochrome P450 (CYP… Expand
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Highly Cited
1996
Highly Cited
1996
Antipyrine has been widely used as a probe drug for human oxidative drug metabolism. To evaluate the role of antipyrine as a… Expand
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Highly Cited
1987
Highly Cited
1987
The elimination of diazepam and antipyrine and the urinary excretion of their metabolites were investigated in 21 healthy… Expand
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Highly Cited
1984
Highly Cited
1984
The effect of liver cirrhosis on plasma clearance and metabolite profile of i.v. administered antipyrine was studied in 23… Expand
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Highly Cited
1983
Highly Cited
1983
A rapid, selective and sensitive method was developed for the determination of antipyrine and its main metabolites in plasma… Expand
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Highly Cited
1982
Highly Cited
1982
1 The influence of enzyme induction with antipyrine and pentobarbitone was studied on the rates of formation of the major… Expand
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Highly Cited
1981
Highly Cited
1981
Adult, male, unmedicated twins received antipyrine orally under carefully controlled environmental conditions. Relative… Expand
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Highly Cited
1979
Highly Cited
1979
1. The amounts of antipyrine and its metabolites excreted in 24 h urine after i.v. injection of 10 mg antipyrine into male Wistar… Expand
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Highly Cited
1974
Highly Cited
1974
Summary Twelve common drugs that are tertiary amines react with nitrite in aqueous solution at ph 3 to 4 to form… Expand
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Highly Cited
1971
Highly Cited
1971
In the previous paper, it was shown that antipyrine was oxidized not only to 4-hydroxyantipyrine, but also to 3-hydroxymethyl-2… Expand
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