Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,741,323 papers from all fields of science
Search
Sign In
Create Free Account
4-amidinoindan-1-one 2'-amidinohydrazone
Known as:
4-AIAH
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
6 relations
Broader (4)
Amidines
Antineoplastic Agents
Enzyme Inhibitors
Indans
Narrower (2)
CGP 48664
SAM 486A
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Polyamine depletion with two different polyamine analogues causes DNA damage in human breast cancer cell lines.
Veronica M. Johansson
,
S. Oredsson
,
K. Alm
DNA and Cell Biology
2008
Corpus ID: 29659129
It is well known that the positively charged polyamines have a DNA-stabilizing function and that polyamine depletion alters…
Expand
2000
2000
The organization of replicon clusters is not affected by polyamine depletion.
K. Alm
,
S. Oredsson
Journal of Structural Biology
2000
Corpus ID: 23348096
Earlier investigations have shown that polyamine depletion affects DNA replication negatively. DNA is synthesized in replicons…
Expand
1998
1998
In vitro manipulation of L1210 cell cycle kinetics with 4-amidinoindan-1-one 2'-amidinohydrazone, alpha-difluoromethylornithine and N1-acetylspermine.
B. Dorhout
,
P. J. Poortenga
,
A. Kingma
,
E. de Hoog
,
F. Muskiet
Biochimica et Biophysica Acta
1998
Corpus ID: 25724144
1997
1997
4-Amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A) exerts in vitro growth inhibitory effects that are not only related to S-adenosylmethionine decarboxylase (SAMdc) inhibition.
B. Dorhout
,
M. Odink
,
E. de Hoog
,
A. Kingma
,
E. van der Veer
,
F. Muskiet
Biochimica et Biophysica Acta
1997
Corpus ID: 11748999
1997
1997
CGP 48664, a potent and specific S-adenosylmethionine decarboxylase inhibitor: effects on regulation and stability of the enzyme.
F. Svensson
,
H. Mett
,
L. Persson
Biochemical Journal
1997
Corpus ID: 36400381
Mammalian S-adenosylmethionine decarboxylase (AdoMetDC) catalyses a regulatory important step in the biosynthesis of polyamines…
Expand
1997
1997
Ordered cell cycle phase perturbations in Chinese hamster ovary cells treated with an S-adenosylmethionine decarboxylase inhibitor.
J. O. Fredlund
,
S. Oredsson
European Journal of Biochemistry
1997
Corpus ID: 24862630
The polyamines putrescine, spermidine, and spermine are needed for normal cell cycle progression and polyamine-depleted cells…
Expand
1995
1995
In vivo growth inhibition of leukemia by 4‐amidinoindan‐1‐one 2′‐amidinohydrazone (CGP 48664a), a new inhibitor of S‐adenosylmethionine decarboxylase
B. Dorhout
,
R. Velde
,
H. Kingma
,
E. de Hoog
,
F. Muskiet
International Journal of Cancer
1995
Corpus ID: 35847003
We studied the in vivo growth‐inhibitory effect of the new S‐adenosylmethionine decarboxylase inhibitor 4‐amidinoindan‐I‐one 2…
Expand
1995
1995
in vivo effects of 4‐amidinoindan‐l‐one 2′‐amidinohydrazone (CGP 48664A) and α‐difluoromethylornithine (DFMO) on L1210 growth, cell‐cycle phase distribution and polyamine contents
B. Dorhout
,
Roelf Jakob Te Velde
,
Harri Ferwerda
,
Anneke W. Kingma
,
E. de Hoog
,
F. Muskiet
International Journal of Cancer
1995
Corpus ID: 11319719
We studied the in vivo effects of 4‐amidinoindan‐l‐one 2′‐amidinohydrazone (CGP 48664A), α‐difluoromethylornithine (DFMO) and a…
Expand
1993
1993
4-Amidinoindan-1-one 2'-amidinohydrazone: a new potent and selective inhibitor of S-Adenosylmethionine decarboxylase.
J. Staněk
,
G. Caravatti
,
+4 authors
U. Regenass
Journal of Medicinal Chemistry
1993
Corpus ID: 39742089
Two isomeric amidino-2-acetylpyridine amidinohydrazones, 11 and 12, and 4-amidinoindanone amidinohydrazone, 17, have been…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE