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3T3-L1 Cells

Known as: Cells, 3T3-L1, 3T3-L1 Cell, 3T3 L1 Cells 
A continuous cell line that is a substrain of SWISS 3T3 CELLS developed though clonal isolation. The mouse fibroblast cells undergo an adipose-like… 
National Institutes of Health

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MicrobiologicalProcess of secretionaspects of radiation effectsphysiological aspects

Papers overview

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2018
2018
Long Noncoding RNA GAS5 Suppresses 3T3-L1 Cells Adipogenesis Through miR-21a-5p/PTEN Signal Pathway.
Emerging studies indicated that both long noncoding RNAs and micro-RNAs play crucial roles in the mediation of adipogenesis… 
Highly Cited
2007
Highly Cited
2007
A Novel Pathway to Enhance Adipocyte Differentiation of 3T3-L1 Cells by Up-regulation of Lipocalin-type Prostaglandin D Synthase Mediated by Liver X Receptor-activated Sterol Regulatory Element…
Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) is expressed in adipocytes and is proposed to be involved in the regulation… 
2004
2004
Dynamic tracking and mobility analysis of single GLUT4 storage vesicle in live 3T3-L1 cells
ABSTRACTGlucose transporter 4 (GLUT4) is responsible for insulin-stimulated glucose transporting into the insulin-sensitive fat… 
2001
2001
Expression of p68 RNA helicase is closely related to the early stage of adipocyte differentiation of mouse 3T3-L1 cells.
We have previously identified the genes expressed early in the differentiation of mouse 3T3-L1 cells into adipocytes. Since these… 
1999
1999
Inhibition of adipogenesis by a COOH-terminally truncated mutant of PPARgamma2 in 3T3-L1 cells.
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear receptor that is thought to be an important regulator… 
1996
1996
Functional expression of thyrotropin receptor in differentiated 3T3-L1 cells: a possible model cell line of extrathyroidal expression of thyrotropin receptor.
Thyrotropin receptor (TSHR) in extrathyroidal tissue, especially fat tissue, is supposed to have important roles in the… 
Highly Cited
1991
Highly Cited
1991
Induction of acyl-CoA-binding protein and its mRNA in 3T3-L1 cells by insulin during preadipocyte-to-adipocyte differentiation.
The induction of acyl-CoA-binding protein (ACBP) and ACBP mRNA was investigated in 3T3-L1 cells during growth and insulin-induced… 
Highly Cited
1990
Highly Cited
1990
Insulin regulation of hexose transport in mouse 3T3-L1 cells expressing the human HepG2 glucose transporter.
Complementary DNA encoding a HepG2 cell-facilitated glucose transporter (GLUT1) was subcloned into a metal-inducible, mammalian… 
Highly Cited
1990
Highly Cited
1990
Development of the hormone-sensitive glucose transport activity in differentiating 3T3-L1 murine fibroblasts. Role of the two transporter species and their subcellular localization.
The development of a hormone-responsive glucose transport activity during differentiation of 3T3-L1 murine fibroblasts to an… 
1987
1987
A putative protein-sequestration site involving intermediate filaments for protein degradation by autophagy. Studies with microinjected purified glycolytic enzymes in 3T3-L1 cells.
Several glycolytic enzymes (lactate dehydrogenase, pyruvate kinase, glyceraldehyde-3-phosphate dehydrogenase) were radiolabelled… 
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