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3,4-Methylenedioxyamphetamine

Known as: 1,3-Benzodioxole-5-ethanamine, alpha-methyl-, MDA, 3,4-Methylenedioxyamphetamine [Chemical/Ingredient] 
An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (6)

2-hydroxy-4,5-methylenedioxyamphetamine3,4-methylenedioxyethamphetamine3,4-methylenedioxyphenethylamine3,4-methylenedioxyphenyl-1-ethanamine

Broader (4)

Adrenergic Uptake InhibitorsAmphetamineHallucinogensSerotonin Agents
Ecstasy - drugIn BloodMethylenedioxyamphetamine:PrThr:Pt:Urine:Ord:Confirmagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability
Cancer stem cells (CSCs) have recently been identified in leukaemia and solid tumours; however, the role of CSCs in metastasis… 
Highly Cited
2008
Highly Cited
2008
Proton-sponge coated quantum dots for siRNA delivery and intracellular imaging.
We report the rational design of multifunctional nanoparticles for short-interfering RNA (siRNA) delivery and imaging based on… 
Highly Cited
2006
Highly Cited
2006
Persistent Activation of Stat3 Signaling Induces Survivin Gene Expression and Confers Resistance to Apoptosis in Human Breast Cancer Cells
Purpose: Signal transducer and activator of transcription 3 (Stat3) protein is persistently activated in breast cancer and… 
Review
2002
Review
2002
Oxidants, antioxidants and carcinogenesis.
Reactive oxygen metabolites (ROMs), such as superoxide anions (O2*-) hydrogen peroxide (H2O2), and hydroxyl radical (*OH… 
Highly Cited
1999
Highly Cited
1999
Effects of silicon on enzyme activity and sodium, potassium and calcium concentration in barley under salt stress
Two contrasting barley (Hordeum vulgare L.) cultivars: Kepin No.7 (salt sensitive), and Jian 4 (salt tolerant) were grown in a… 
Highly Cited
1997
Highly Cited
1997
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic…
Advanced glycation end products (AGEs) include a variety of protein adducts whose accumulation alters the structure and function… 
Highly Cited
1990
Highly Cited
1990
Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.
Antisera and monoclonal antibodies generated against autologous malondialdehyde-conjugated low density lipoprotein (MDA-LDL), 4… 
Highly Cited
1988
Highly Cited
1988
Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity
The psychotropic amphetamine derivatives 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA) have… 
Highly Cited
1987
Highly Cited
1987
3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin…
This study examines the effects of repeated systemic administration (20 mg/kg s.c., twice daily for 4 days) of 3,4… 
Highly Cited
1980
Highly Cited
1980
Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages.
Glutaraldehyde treatment of (125)I-labeled low density lipoprotein ((125)I-native-LDL) produced a modified LDL ((125)I-glut-LDL… 
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