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2-methylcitrate

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2016
024619752016

Related topics

Related topics

3 relations
2-Methylcitrate:SCnc:Pt:Amnio fld:Qn

Broader (2)

2-methylcitric acidCitric Acid

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
2-methylcitrate
Citric Acid
2-methylcitric acid
2-Methylcitrate:SCnc:Pt:Amnio fld:Qn

Papers overview

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2010
2010
In Salmonella enterica, 2-methylcitrate blocks gluconeogenesis.
Strains of Salmonella enterica serovar Typhimurium LT2 lacking a functional 2-methylcitric acid cycle (2-MCC) display increased… (More)
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2002
2002
Identification of two prpDBC gene clusters in Corynebacterium glutamicum and their involvement in propionate degradation via the 2-methylcitrate cycle.
Genome sequencing revealed that the Corynebacterium glutamicum genome contained, besides gltA, two additional citrate synthase… (More)
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Highly Cited
2002
Highly Cited
2002
Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity.
Methylmalonic acidurias are biochemically characterized by an accumulation of methylmalonate (MMA) and alternative metabolites… (More)
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2002
2002
Pentaerythritol propoxylate: a new crystallization agent and cryoprotectant induces crystal growth of 2-methylcitrate dehydratase.
In the search for macromolecular crystallization conditions, the precipitant is probably the most important variable, such that… (More)
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2001
2001
In vitro conversion of propionate to pyruvate by Salmonella enterica enzymes: 2-methylcitrate dehydratase (PrpD) and aconitase Enzymes catalyze the conversion of 2-methylcitrate to 2-methylisocitrate…
Salmonella enterica serovar Typhimurium LT2 catabolizes propionate through the 2-methylcitric acid cycle, but the identity of the… (More)
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2001
2001
Studies of propionate toxicity in Salmonella enterica identify 2-methylcitrate as a potent inhibitor of cell growth.
Salmonella enterica serovar Typhimurium LT2 showed increased sensitivity to propionate when the 2-methylcitric acid cycle was… (More)
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2000
2000
The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism.
The Saccharomyces cerevisiae ICL1 gene encodes isocitrate lyase, an essential enzyme for growth on ethanol and acetate. Previous… (More)
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1999
1999
Salmonella typhimurium LT2 catabolizes propionate via the 2-methylcitric acid cycle.
We previously identified the prpBCDE operon, which encodes catabolic functions required for propionate catabolism in Salmonella… (More)
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1998
1998
Citrate synthase and 2-methylcitrate synthase: structural, functional and evolutionary relationships.
Following the complete sequencing of the Escherichia coli genome, it has been shown that the proposed second citrate synthase of… (More)
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1975
1975
Effect of 2-Methylcitrate on Citrate Metabolism: Implications for the Management of Patients with Propionic acidemia and Methylmalonic aciduria
Extract: 2-Methylcitrate was tested in vitro on enzymes which interact with citrate and isocitrate. It was found to inhibit… (More)
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