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2-methylcitrate

 
National Institutes of Health

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Broader (2)

2-methylcitric acidCitric Acid

Papers overview

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Highly Cited
2015
Highly Cited
2015
Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment
Mycobacterium tuberculosis (Mtb) relies on a specialized set of metabolic pathways to support growth in macrophages. By… Expand
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2012
2012
Relationship between vitamin B12 and sensory and motor peripheral nerve function in older adults.
OBJECTIVES To examine whether deficient B12 status or low serum B12 levels are associated with worse sensory and motor peripheral… Expand
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2010
2010
In Salmonella enterica, 2-methylcitrate blocks gluconeogenesis.
Strains of Salmonella enterica serovar Typhimurium LT2 lacking a functional 2-methylcitric acid cycle (2-MCC) display increased… Expand
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Highly Cited
2008
Highly Cited
2008
Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus
A filamentous fungus Aspergillus terreus produces itaconic acid, which is predicted to be derived from cis-aconitic acid via… Expand
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2004
2004
2-Methylcitrate-dependent activation of the propionate catabolic operon (prpBCDE) of Salmonella enterica by the PrpR protein.
The function of the PrpR protein of Salmonella enterica serovar Typhimurium LT2 was studied in vitro and in vivo. The PrpR… Expand
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Highly Cited
2002
Highly Cited
2002
Identification of two prpDBC gene clusters in Corynebacterium glutamicum and their involvement in propionate degradation via the 2-methylcitrate cycle.
Genome sequencing revealed that the Corynebacterium glutamicum genome contained, besides gltA, two additional citrate synthase… Expand
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2002
2002
Identification of the 2-methylcitrate pathway involved in the catabolism of propionate in the polyhydroxyalkanoate-producing strain Burkholderia sacchari IPT101(T) and analysis of a mutant…
Burkholderia sacchari IPT101(T) induced the formation of 2-methylcitrate synthase and 2-methylisocitrate lyase when it was… Expand
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Highly Cited
2000
Highly Cited
2000
The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism.
The Saccharomyces cerevisiae ICL1 gene encodes isocitrate lyase, an essential enzyme for growth on ethanol and acetate. Previous… Expand
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1998
1998
Citrate synthase and 2-methylcitrate synthase: structural, functional and evolutionary relationships.
Following the complete sequencing of the Escherichia coli genome, it has been shown that the proposed second citrate synthase of… Expand
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1975
1975
Effect of 2-Methylcitrate on Citrate Metabolism: Implications for the Management of Patients with Propionic acidemia and Methylmalonic aciduria
Extract: 2-Methylcitrate was tested in vitro on enzymes which interact with citrate and isocitrate. It was found to inhibit… Expand
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