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2-methylcitric acid

Known as: 3-carboxy-3-hydroxy-2-methylpentanedioic acid, methylcitric acid 
National Institutes of Health

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2-methylcitrate

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Citrates

Papers overview

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2017
2017
First Biochemical Characterization of a Methylcitric Acid Cycle from Bacillus subtilis Strain 168.
The genome of Bacillus subtilis strain 168 contains the mother cell metabolic gene (mmg) operon that encodes homologues from the… 
2009
2009
Disruption of the 2-methylcitric acid cycle and evaluation of poly-3-hydroxybutyrate-co-3-hydroxyvalerate biosynthesis suggest alternate catabolic pathways of propionate in Burkholderia sacchari.
The objective of the present work was to evaluate the relevance of the 2-methylcitric acid cycle (2MCC) to the catabolism of… 
2003
2003
Serum levels of total homocysteine, homocysteine metabolites and of advanced glycation end-products (AGEs) in patients after renal transplantation.
AIMS Hyperhomocysteinemia has been described as an independent risk factor for cardiovascular diseases (CVD) influencing patient… 
2002
2002
Rapid and sensitive method for prenatal diagnosis of propionic acidemia using stable isotope dilution gas chromatography-mass spectrometry and urease pretreatment.
  • Y. InoueT. Kuhara
  • Journal of chromatography. B, Analytical…
  • 2002
  • Corpus ID: 31599893
Highly Cited
2002
Highly Cited
2002
Identification of the 2-Methylcitrate Pathway Involved in the Catabolism of Propionate in the Polyhydroxyalkanoate-Producing Strain Burkholderia sacchari IPT101T and Analysis of a Mutant Accumulating…
ABSTRACT Burkholderia sacchari IPT101T induced the formation of 2-methylcitrate synthase and 2-methylisocitrate lyase when it was… 
1996
1996
Relationship among homocyst(e)ine, vitamin B-12 and cardiac disease in the elderly: association between vitamin B-12 deficiency and decreased left ventricular ejection fraction.
We evaluated the association of moderate hyperhomocyst(e)inemia and vitamin B-12 status with coronary artery disease (CAD) and… 
1994
1994
Identification of the stereoisomeric configurations of methylcitric acid produced bysi-citrate synthase and methylcitrate synthase using capillary gas chromatography-mass spectrometry
SummaryThe absolute separation of the four stereoisomeric configurations of methylcitric acid can be achieved on a nonchiral… 
1990
1990
Early amniocentesis and amniotic fluid organic acid levels in the prenatal diagnosis of organic acidemias.
1989
1989
Methylcitrate in maternal urine during a pregnancy with a fetus affected with propionic acidaemia
SummaryPatients homozygous for propionic acidaemia have high levels of methylcitric acid in urine while heterozygotes have normal… 
1977
1977
Identification of D-threo-alpha-methylisocitrate as stereochemically specific substrate for bovine heart aconitase and inhibitor of TPN-linked isocitrate dehydrogenase.
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