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2-hydroxyestrone

Known as: Estra-1,3,5(10-trien-17-one, 2,3-dihydroxy)-, 2-OHE(1), Estra-1,3,5(1)-Trien-17-One, 2,3-Dihydroxy- 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 2 by cytochrome P450 (CYP… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Estrogens and estrogen metabolites have important functions in cardiovascular and other physiology, yet the patterns of estrogen… Expand
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Highly Cited
2003
Highly Cited
2003
We systematically characterized the oxidative metabolites of 17beta-estradiol and estrone formed by 15 human cytochrome P450 (CYP… Expand
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Highly Cited
2001
Highly Cited
2001
The oxidative metabolism of 17beta-estradiol (E2) and estrone (E1) to catechol estrogens (2-OHE2, 4-OHE2, 2-OHE1, and 4-OHE1) and… Expand
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Highly Cited
2000
Highly Cited
2000
Experimental and clinical evidence suggests that 16alpha-hydroxylated estrogen metabolites, biologically strong estrogens, are… Expand
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Highly Cited
2000
Highly Cited
2000
Asian diets high in soy are associated with lower risk for breast cancer compared with Western diets. Moreover, higher levels of… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND It has been suggested that women who metabolize a larger proportion of their endogenous estrogen via the 16alpha… Expand
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Review
1996
Review
1996
The issue of the role of 2-hydroxyestrone (2-OHE1) in breast cancer has been the subject of considerable controversy as to… Expand
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Highly Cited
1995
Highly Cited
1995
Xenobiotic estrogens are external compounds with estrogenic activity that may thereby affect the risk of breast cancer. This… Expand
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1994
1994
Alterations in the metabolism of estrogen have been implicated as an important factor in the etiology of diseases such as… Expand
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Highly Cited
1984
Highly Cited
1984
The estrogen responsive human breast cancer MCF-7 cell culture was examined for its response to 2-hydroxyestrone a principal… Expand
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