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2-hydroxyestrone

Known as: Estra-1,3,5(10-trien-17-one, 2,3-dihydroxy)-, 2-OHE(1), Estra-1,3,5(1)-Trien-17-One, 2,3-Dihydroxy- 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 2 by cytochrome P450 (CYP… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Anticarcinogenic AgentsHydroxyestrones
NCIt Antineoplastic Agent Terminology

Papers overview

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Highly Cited
1994
Highly Cited
1994
Catechol estrogen production in rat microsomes after treatment with indole-3-carbinol, ascorbigen, or β-naphthaflavone: A comparison of stable isotope dilution gas chromatography-mass spectrometry…
Highly Cited
1992
Highly Cited
1992
Synthesis and characterization of estrogen 2,3- and 3,4-quinones. Comparison of DNA adducts formed by the quinones versus horseradish peroxidase-activated catechol estrogens.
Catechol estrogens (CE) are among the major metabolites of estrone (E1) and 17 beta-estradiol (E2). Oxidation of these… 
Highly Cited
1990
Highly Cited
1990
Stopped-flow investigation of antioxidant activity of estrogens in solution.
Highly Cited
1989
Highly Cited
1989
Opposite effects of estrogen and catecholestrogen on hormone-sensitive breast cancer cell growth and differentiation
1980
1980
Rapid metabolic clearance of the catechol estrogen 2-hydroxyestrone.
The plasma metabolic clearance rate (MCRp) of 2-hydroxyestrone was measured in normal young adults by two methods: infusion of… 
Highly Cited
1976
Highly Cited
1976
Cytochrome P-450-mediated oxidation of 2-hydroxyestrogens to reactive intermediates.
Highly Cited
1976
Highly Cited
1976
Convenient large scale preparation of catechol estrogens
Highly Cited
1975
Highly Cited
1975
The excretion of 2-hydroxyestrone during the menstrual cycle.
A double isotope derivative determination technique was developed to investigate the excretion of 2-hydroxyestrone inhuman… 
Highly Cited
1973
Highly Cited
1973
A simple chemical method for the synthesis of catechol estrogens.
Highly Cited
1971
Highly Cited
1971
Radioimmunoassay of 2-hydroxyestrone in human plasma.
ABSTRACT Rabbit anti-2-hydroxyestrone antiserum was obtained using 2-hydroxyestrone coupled to bovine serum albumin as the… 
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