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2-hydroxyestrone

Known as: Estra-1,3,5(10-trien-17-one, 2,3-dihydroxy)-, 2-OHE(1), Estra-1,3,5(1)-Trien-17-One, 2,3-Dihydroxy- 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 2 by cytochrome P450 (CYP… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Anticarcinogenic AgentsHydroxyestrones
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Obesity, hormone therapy, estrogen metabolism and risk of postmenopausal breast cancer
Hormone therapy (HT) and body mass index (BMI) have been associated with postmenopausal breast cancer. Because estrogen… 
Highly Cited
1994
Highly Cited
1994
Catechol estrogen production in rat microsomes after treatment with indole-3-carbinol, ascorbigen, or β-naphthaflavone: A comparison of stable isotope dilution gas chromatography-mass spectrometry…
Highly Cited
1992
Highly Cited
1992
Synthesis and characterization of estrogen 2,3- and 3,4-quinones. Comparison of DNA adducts formed by the quinones versus horseradish peroxidase-activated catechol estrogens.
Catechol estrogens (CE) are among the major metabolites of estrone (E1) and 17 beta-estradiol (E2). Oxidation of these… 
Highly Cited
1990
Highly Cited
1990
Stopped-flow investigation of antioxidant activity of estrogens in solution.
Highly Cited
1989
Highly Cited
1989
Opposite effects of estrogen and catecholestrogen on hormone-sensitive breast cancer cell growth and differentiation
1980
1980
Rapid metabolic clearance of the catechol estrogen 2-hydroxyestrone.
The plasma metabolic clearance rate (MCRp) of 2-hydroxyestrone was measured in normal young adults by two methods: infusion of… 
Highly Cited
1976
Highly Cited
1976
Cytochrome P-450-mediated oxidation of 2-hydroxyestrogens to reactive intermediates.
Highly Cited
1976
Highly Cited
1976
Convenient large scale preparation of catechol estrogens
Highly Cited
1975
Highly Cited
1975
The excretion of 2-hydroxyestrone during the menstrual cycle.
A double isotope derivative determination technique was developed to investigate the excretion of 2-hydroxyestrone inhuman… 
Highly Cited
1971
Highly Cited
1971
Radioimmunoassay of 2-hydroxyestrone in human plasma.
ABSTRACT Rabbit anti-2-hydroxyestrone antiserum was obtained using 2-hydroxyestrone coupled to bovine serum albumin as the… 
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