2-hydroxyestrone

Known as: Estra-1,3,5(10-trien-17-one, 2,3-dihydroxy)-, 2-OHE(1), Estra-1,3,5(1)-Trien-17-One, 2,3-Dihydroxy- 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 2 by cytochrome P450 (CYP… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1960-2017
051019602017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
We systematically characterized the oxidative metabolites of 17beta-estradiol and estrone formed by 15 human cytochrome P450 (CYP… (More)
Is this relevant?
2000
2000
Asian diets high in soy are associated with lower risk for breast cancer compared with Western diets. Moreover, higher levels of… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Experimental and clinical evidence suggests that 16alpha-hydroxylated estrogen metabolites, biologically strong estrogens, are… (More)
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1999
Highly Cited
1999
BACKGROUND It has been suggested that women who metabolize a larger proportion of their endogenous estrogen via the 16alpha… (More)
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
1998
1998
Metabolism of estradiol occurs via two mutually exclusive hydroxylative pathways, yielding metabolites of divergent biological… (More)
Is this relevant?
1997
1997
Rapid and simple enzyme immunoassays (EIAs) were recently developed to measure 2-hydroxyestrone and 16alpha-hydroxyestrone in… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
1996
1996
Estrogens can have two roles in the induction of cancer: stimulating proliferation of cells by receptor-mediated processes, and… (More)
Is this relevant?
1995
1995
Xenobiotic estrogens are external compounds with estrogenic activity that may thereby affect the risk of breast cancer. This… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1994
1994
Alterations in the metabolism of estrogen have been implicated as an important factor in the etiology of diseases such as… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
The estrogen responsive human breast cancer MCF-7 cell culture was examined for its response to 2-hydroxyestrone a principal… (More)
  • figure 1
  • figure 2
  • figure 6
  • figure 5
Is this relevant?