FAQ

2-amino-1,3,4-thiadiazole

Known as: Aminothiadiazole, Amino 134-Thiadiazole, 1,3, 4-Thiadiazole, 2-amino- (8CI) 
A synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase… (More)

Topic mentions per year

Topic mentions per year

1960-2016
024619602016

Related topics

Related topics

3 relations

Broader (2)

Antineoplastic AgentsThiadiazoles

Narrower (1)

NSC 4728

Related mentions per year

Related mentions per year

1947-2018
19401960198020002020
2-amino-1,3,4-thiadiazole
Antineoplastic Agents
Thiadiazoles
NSC 4728

Papers overview

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2014
2014
Comparison of the hydrogen-bond patterns in 2-amino-1,3,4-thiadiazolium hydrogen oxalate, 2-amino-1,3,4-thiadiazole-succinic acid (1/2), 2-amino-1,3,4-thiadiazole-glutaric acid (1/1) and 2-amino-1,3…
The X-ray single-crystal structure determinations of the chemically related compounds 2-amino-1,3,4-thiadiazolium hydrogen… (More)
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2013
2013
Neuroprotective activity of 2-amino-1,3,4-thiadiazole derivative 4BrABT--an in vitro study.
4BrABT (2-(4-Bromophenylamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole) is a compound known for its interesting in vitro… (More)
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2011
2011
The activity of a new 2-amino-1,3,4-thiadiazole derivative 4ClABT in cancer and normal cells.
The 2-amino-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole set are well known compounds with interesting in vitro and in vivo anti… (More)
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2007
2007
Anticancer, neuroprotective activities and computational studies of 2-amino-1,3,4-thiadiazole based compound.
Anticancer activity studies of 2-(4-fluorophenylamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole (FABT), as one of the most… (More)
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1993
1993
Synthesis and local anesthetic activity of alkylaminoacyl derivatives of 2-amino-1,3,4-thiadiazole.
We prepared some series of 2-(alkylaminoacyl) derivatives of 2-amino-1,3,4-thiadiazoles. Most terms were subjected to a… (More)
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1986
1986
Clinical and clinical pharmacologic studies of 2-amino-1,3,4-thiadiazole (A-TDA:NSC 4728)
A clinical phase I–II evaluation of 2-amino-1,3,4-thiadiazole (A-TDA) administered daily, twice a week, or weekly was undertaken… (More)
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1980
1980
The pharmacologic fate of the antitumor agent 2-amino-1,3,4-thiadiazole in the dog
Anticipating the renewed clinical trial of the antitumor agent 2-amino-1,3,4-thiadiazole (AT, NSC-4728), we have studied the… (More)
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1979
1979
Pharmacokinetic model for 2-amino-1,3,4-thiadiazole in mouse, dog, and monkey.
A mathematic model has been developed to describe the time course of 2-amino-1,3,4-thiadiazole and its metabolites in the serum… (More)
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1977
1977
Mechanism of action of 2-amino-1,3,4-thiadiazole (NSC 4728).
The synthesis and isolation of two derivatives of 2-amino-1,3,4-thialdiazole(aminothiadiazole) are described. The derivatives are… (More)
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1976
1976
Effects of 2-amino-1,3,4-thiadiazole on ribonucleotide pools of leukemia L1210 cells.
The effects of 2-amino-1,3,4-thiadiazole [aminothiadiazole (NSC 4728)] on purine and pyrimidine ribonucleotide pools of L1210… (More)
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