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2,3-dinor-6-ketoprostaglandin F1alpha

Known as: Pgi2-M, 2,3-Dkpgf1alpha, Cyclopentanepentanoic Acid, 3,5-Dihydroxy-2-((1E,3S)-3-Hydroxy-1-Octenyl)-Gamma-Oxo-, (1R,2R,3R,5S)- 
A beta-oxidation product of 6-keto prostaglandin F1 alpha (PGF1a) and the major urinary metabolite of prostaglandin I2 (prostacyclin, PGI2). 2,3… 
National Institutes of Health

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2 relations

Broader (1)

6-Ketoprostaglandin F1 alpha
analogs & derivatives

Papers overview

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Highly Cited
2007
Highly Cited
2007
Oxo- and imidovanadium complexes incorporating methylene- and dimethyleneoxa-bridged calix[3]- and -[4]arenes: synthesis, structures and ethylene polymerisation catalysis.
Reaction of [V(X)(OR)3] (X=O, Np-tolyl; R=Et, nPr or tBu) with p-tert-butylhexahomotrioxacalix[3]areneH3, LH3, affords the air… 
2005
2005
Peroxynitrite provides the peroxide tone for PGHS‐2‐dependent prostacyclin synthesis in vascular smooth muscle cells
Endotoxin‐treated vascular smooth muscle cells (VSMCs) were recently shown to release high amounts of prostacyclin (PGI2… 
Highly Cited
1999
Highly Cited
1999
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin
Spinal prostanoids are implicated in the development of thermal hyperalgesia after peripheral injury, but the specific prostanoid… 
Highly Cited
1998
Highly Cited
1998
Effects of various doses of antithrombin III on endotoxin-induced endothelial cell injury and coagulation abnormalities in rats.
Highly Cited
1998
Highly Cited
1998
Calcium-Dependent Phospholipase A2 Mediates the Production of Endothelium-Derived Hyperpolarizing Factor in Perfused Rat Mesenteric Prearteriolar Bed
The isolated, perfused rat mesenteric bed releases a cytochrome P450-linked metabolite of arachidonic acid (AA) as endothelium… 
Highly Cited
1996
Highly Cited
1996
Production and localization of cGMP and PGE2 in nitroprusside-stimulated rat colonic ion transport.
Nitrovasodilators, such as sodium nitroprusside (SNP), release nitric oxide (NO) and stimulate intestinal electrolyte transport… 
Highly Cited
1985
Highly Cited
1985
Thromboxane (TX)A3 and prostaglandin (PG)I3 are formed in man after dietary eicosapentaenoic acid: identification and quantification by capillary gas chromatography-electron impact mass spectrometry.
The low incidence of myocardial infarction in Greenland Eskimos has been related to their traditional marine diet rich in… 
Highly Cited
1978
Highly Cited
1978
Synthesis of prostaglandin 6-keto F1alpha by cultured aortic smooth muscle cells and stimulation of its formation in a coupled system with platelet lysates.
Highly Cited
1978
Highly Cited
1978
Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography.
Highly Cited
1978
Highly Cited
1978
Pharmacological activity of PGI2 and its metabolite 6-oxo-PGF1alpha on human uterus and fallopian tubes.
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