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2,3-dinor-6-ketoprostaglandin F1alpha
Known as:
Pgi2-M
, 2,3-Dkpgf1alpha
, Cyclopentanepentanoic Acid, 3,5-Dihydroxy-2-((1E,3S)-3-Hydroxy-1-Octenyl)-Gamma-Oxo-, (1R,2R,3R,5S)-
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A beta-oxidation product of 6-keto prostaglandin F1 alpha (PGF1a) and the major urinary metabolite of prostaglandin I2 (prostacyclin, PGI2). 2,3…
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
6-Ketoprostaglandin F1 alpha
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Cyclooxygenase-2 Promotes Early Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice
M. Burleigh
,
V. Babaev
,
+7 authors
M. Linton
Circulation
2002
Corpus ID: 3104575
Background—Atherosclerosis has features of an inflammatory disease. Because cyclooxygenase (COX)-2 is expressed in…
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Highly Cited
2002
Highly Cited
2002
Inducible Nitric Oxide Synthase Modulates Cyclooxygenase-2 Activity in the Heart of Conscious Rabbits During the Late Phase of Ischemic Preconditioning
K. Shinmura
,
Y. Xuan
,
+4 authors
R. Bolli
Circulation Research
2002
Corpus ID: 17741866
Cyclooxygenase-2 (COX-2) is known to mediate the cardioprotective effects of the late phase of ischemic preconditioning (PC…
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Highly Cited
1999
Highly Cited
1999
Elevated CSF prostaglandin E2 levels in patients with probable AD.
T. Montine
,
K. Sidell
,
+4 authors
J. Morrow
Neurology
1999
Corpus ID: 11212579
OBJECTIVE To determine CSF eicosanoid concentrations and brain cyclo-oxygenase activity in AD patients and age-matched control…
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Highly Cited
1999
Highly Cited
1999
Acetaminophen inhibits spinal prostaglandin E2 release after peripheral noxious stimulation.
U. Muth‐Selbach
,
I. Tegeder
,
K. Brune
,
G. Geisslinger
Anesthesiology
1999
Corpus ID: 11803129
BACKGROUND Prostaglandin play a pivotal role in spinal nociceptive processing. At therapeutic concentrations, acetaminophen is…
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Highly Cited
1998
Highly Cited
1998
Upregulation of prostacyclin synthesis-related gene expression by shear stress in vascular endothelial cells.
K. Okahara
,
Bing Sun
,
Jun-ichi Kambayashi
Arteriosclerosis, Thrombosis and Vascular Biology
1998
Corpus ID: 6767641
Prostacyclin (prostaglandin I2, PGI2) has a variety of functions, including inhibition of smooth muscle cell proliferation…
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Highly Cited
1997
Highly Cited
1997
Involvement of NF‐κB in the regulation of cyclooxygenase‐2 protein expression in LPS‐stimulated J774 macrophages
F. D’Acquisto
,
T. Iuvone
,
L. Rombolà
,
L. Sautebin
,
M. Di Rosa
,
R. Carnuccio
FEBS Letters
1997
Corpus ID: 6989017
Highly Cited
1997
Highly Cited
1997
Low-dose aspirin in prevention of miscarriage in women with unexplained or autoimmune related recurrent miscarriage: effect on prostacyclin and thromboxane A2 production.
M. Tulppala
,
M. Marttunen
,
+4 authors
O. Ylikorkala
Human Reproduction
1997
Corpus ID: 35501671
Early pregnancies in women with a history of recurrent spontaneous abortion (RSA) are accompanied by a deficiency in vasodilatory…
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Highly Cited
1978
Highly Cited
1978
Chemical stability of prostacyclin (PGI2) in aqueous solutions.
M. Cho
,
M. Allen
Prostaglandins
1978
Corpus ID: 2057799
Highly Cited
1978
Highly Cited
1978
Pulmonary and systemic vasodilator effects of the newly discovered prostaglandin, PGI2.
P. Kadowitz
,
B. Chapnick
,
L. Feigen
,
A. Hyman
,
P. K. Nelson
,
E. Spannhake
Journal of applied physiology: respiratory…
1978
Corpus ID: 24858082
The effects of the newly discovered bicyclic prostaglandin, prostacyclin (PGI2), on the pulmonary and systemic vascular beds were…
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Highly Cited
1976
Highly Cited
1976
The chemical structure of prostaglandin X (prostacyclin).
Roy A. Johnson
,
D. Morton
,
+8 authors
J. R. Vane
Prostaglandins
1976
Corpus ID: 28859389
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