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16alpha-Hydroxyestrone

Known as: Hydroxyestrone-16alpha, 16 Alpha OHE, Estra-1,3,5(10)-Triene-3,16alpha-Diol-17-One 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 16 by cytochrome P450 (CYP… 
National Institutes of Health

Papers overview

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2008
2008
Application of comprehensive two-dimensional gas chromatography to sterols analysis.
2008
2008
Involvement of peroxiredoxin IV in the 16α‐hydroxyestrone‐induced proliferation of human MCF‐7 breast cancer cells
2006
2006
Comparison of plasma and urinary levels of 2-hydroxyestrogen and 16 alpha-hydroxyestrogen metabolites.
2001
2001
Evaluation of an EIA method for measuring serum levels of the estrogen metabolite 2-hydroxyestrone in adults
Highly Cited
2000
Highly Cited
2000
Involvement of genotoxic effects in the initiation of estrogen‐induced cellular transformation: Studies using Syrian hamster embryo cells treated with 17β‐estradiol and eight of its metabolites
To examine a direct involvement of genotoxic effects of estrogens in the initiation of hormonal carcinogenesis, the abilities of… 
2000
2000
Estrone and estradiol metabolism in vivo in human breast cysts☆ 1 1 ☆ A preliminary report was presented at the 45th Annual Meeting of the Society for Gynecologic Investigation, March 11–14…
Highly Cited
2000
Highly Cited
2000
The effect of flaxseed and wheat bran consumption on urinary estrogen metabolites in premenopausal women.
Estrogen is metabolized along two competing pathways to form the 2-hydroxylated and the 16alpha-hydroxylated metabolites. Based… 
1999
1999
Within-person variability of the ratios of urinary 2-hydroxyestrone to 16α-hydroxyestrone in Caucasian women☆
1988
1988
Mineralization Ages of the Inakuraishi and Ohe Ore Deposits, Southwestern Hokkaido, Japan
In the Inakuraishi-Ohe mining district, there are successive mineralizations from the kuroko-type to polymetallic and iron… 
1985
1985
Increased levels of 16 alpha-hydroxyestrone-modified proteins in pregnancy and in systemic lupus erythematosus.
The ketolic estrogen 16 alpha-hydroxyestrone (16 alpha OHE) reacts with lysine residues, forming stable covalent adducts with… 
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