16alpha-Hydroxyestrone

Known as: Hydroxyestrone-16alpha, 16 Alpha OHE, Estra-1,3,5(10)-Triene-3,16alpha-Diol-17-One 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 16 by cytochrome P450 (CYP… (More)
National Institutes of Health

Papers overview

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2005
2005
OBJECTIVES Estrogen is metabolized in the body through two mutually exclusive pathways yielding metabolites with different… (More)
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Review
2004
Review
2004
Sex hormones seem to play an important role as modulators of the autoimmune disease onset/perpetuation. Generally, steroid… (More)
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Highly Cited
2004
Highly Cited
2004
Women with high circulating estrogen concentrations have an increased risk of breast cancer; thus, it is important to understand… (More)
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2003
2003
Studies of circulating estrogen levels in relation to pre-menopausal breast cancer risk have yielded inconsistent results… (More)
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2001
2001
It has been suggested that alterations in estradiol (E(2)) metabolism, resulting in increased production of 16alpha… (More)
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2001
2001
2-Hydroxyestrone (2-OHE(1)) and 16alpha-hydroxyestrone (16alpha-OHE(1)) have been reported to be risk factors for negative bone… (More)
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Highly Cited
2000
Highly Cited
2000
Experimental and clinical evidence suggests that 16alpha-hydroxylated estrogen metabolites, biologically strong estrogens, are… (More)
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Highly Cited
2000
Highly Cited
2000
Asian diets high in soy are associated with lower risk for breast cancer compared with Western diets. Moreover, higher levels of… (More)
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2000
2000
There is considerable controversy regarding the role of estrogen metabolites in breast cancer risk, fueled in part by the… (More)
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1997
1997
Rapid and simple enzyme immunoassays (EIAs) were recently developed to measure 2-hydroxyestrone and 16alpha-hydroxyestrone in… (More)
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