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16alpha-Hydroxyestrone

Known as: Hydroxyestrone-16alpha, 16 Alpha OHE, Estra-1,3,5(10)-Triene-3,16alpha-Diol-17-One 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 16 by cytochrome P450 (CYP… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Absolute and relative concentrations of estrogens and estrogen metabolites are important for clinical decisions as well as for… Expand
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Highly Cited
2006
Highly Cited
2006
Estrogen and its metabolites are believed to play important roles in breast cancer. The influence of genetic polymorphisms in the… Expand
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Review
2004
Review
2004
Sex hormones seem to play an important role as modulators of the autoimmune disease onset/perpetuation. Generally, steroid… Expand
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Highly Cited
2004
Highly Cited
2004
Women with high circulating estrogen concentrations have an increased risk of breast cancer; thus, it is important to understand… Expand
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Highly Cited
2003
Highly Cited
2003
Background Women who metabolize a large proportion of their estrogen via the 16&agr; hydroxylation pathway could be at a higher… Expand
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Highly Cited
2003
Highly Cited
2003
Studies of circulating estrogen levels in relation to pre-menopausal breast cancer risk have yielded inconsistent results… Expand
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Highly Cited
2000
Highly Cited
2000
Experimental and clinical evidence suggests that 16&agr;-hydroxylated estrogen metabolites, biologically strong estrogens, are… Expand
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Highly Cited
2000
Highly Cited
2000
Asian diets high in soy are associated with lower risk for breast cancer compared with Western diets. Moreover, higher levels of… Expand
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Highly Cited
2000
Highly Cited
2000
There is considerable controversy regarding the role of estrogen metabolites in breast cancer risk, fueled in part by the… Expand
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Highly Cited
1998
Highly Cited
1998
Abstract Increased 16β-hydroxylation of estradiol has been shown to be associated with heightened cancer risk in estrogen… Expand
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