Skip to search formSkip to main contentSkip to account menu

16alpha-Hydroxyestrone

Known as: Hydroxyestrone-16alpha, 16 Alpha OHE, Estra-1,3,5(10)-Triene-3,16alpha-Diol-17-One 
A metabolite formed during the catabolism of estrone by the liver through the hydroxylation of the carbon at position 16 by cytochrome P450 (CYP… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Comparison of Liquid Chromatography-Tandem Mass Spectrometry, RIA, and ELISA Methods for Measurement of Urinary Estrogens
Absolute and relative concentrations of estrogens and estrogen metabolites are important for clinical decisions as well as for… 
Highly Cited
2006
Highly Cited
2006
CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal.
Highly Cited
2004
Highly Cited
2004
Association of CYP17, CYP19, CYP1B1, and COMT Polymorphisms with Serum and Urinary Sex Hormone Concentrations in Postmenopausal Women
Women with high circulating estrogen concentrations have an increased risk of breast cancer; thus, it is important to understand… 
Highly Cited
2004
Highly Cited
2004
Microwave-assisted extraction followed by gas chromatography-mass spectrometry for the determination of endocrine disrupting chemicals in river sediments.
Review
2004
Review
2004
Synovial fluid estrogens in rheumatoid arthritis.
Highly Cited
2004
Highly Cited
2004
Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post-menopausal women in relation to daidzein-metabolizing phenotypes
Highly Cited
2003
Highly Cited
2003
Predictors of the plasma ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone among pre-menopausal, nulliparous women from four ethnic groups.
Studies of circulating estrogen levels in relation to pre-menopausal breast cancer risk have yielded inconsistent results… 
Highly Cited
2002
Highly Cited
2002
In vitro pro- and antioxidant properties of estrogens
Highly Cited
2000
Highly Cited
2000
Increased urinary excretion of 2-hydroxyestrone but not 16alpha-hydroxyestrone in premenopausal women during a soya diet containing isoflavones.
Asian diets high in soy are associated with lower risk for breast cancer compared with Western diets. Moreover, higher levels of… 
Highly Cited
1998
Highly Cited
1998
Estrogen Metabolism and the Malignant Potential of Human Papillomavirus Immortalized Keratinocytes
Abstract Increased 16β-hydroxylation of estradiol has been shown to be associated with heightened cancer risk in estrogen… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)