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16,16-Dimethyl Prostaglandin E2

Known as: dmPGE2 
A stable derivative of prostaglandin E2 (PGE2) with potential hematopoietic activity. Administration of 16,16 dimethyl-prostaglandin E2 (dmPGE2… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation.
Prostaglandin E2 (PGE2) synthesis modulates the response to radiation injury in the mouse intestinal epithelium through effects… 
Highly Cited
2002
Highly Cited
2002
16,16-Dimethyl Prostaglandin E2 Inhibits Indomethacin-Induced Small Intestinal Lesions Through EP3 and EP4 Receptors
We evaluated the effect of various PGE analogs specific to EP receptor subtypes on indomethacin-induced small intestinal lesions… 
Highly Cited
1990
Highly Cited
1990
Luminal surface hydrophobicity of canine gastric mucosa is dependent on a surface mucous gel.
Highly Cited
1988
Highly Cited
1988
Prostaglandin protection of human isolated gastric glands against indomethacin and ethanol injury. Evidence for direct cellular action of prostaglandin.
Isolated human gastric glands from surgical specimens were preincubated in an oxygenated medium with placebo or 16,16 dimethyl… 
Highly Cited
1987
Highly Cited
1987
16,16-Dimethyl prostaglandin E2 increases survival in mice following irradiation.
16,16-Dimethyl prostaglandin E2 (DiPGE2), a stable analog of PGE2, increases the LD50/30 survival in CD2F1 male mice when given… 
Highly Cited
1984
Highly Cited
1984
Histologic and microcirculatory changes in alcohol-induced gastric lesions in the rat: effect of prostaglandin cytoprotection.
Highly Cited
1984
Highly Cited
1984
Effect of 16,16 dimethyl prostaglandin E2 on aspirin induced damage to rat gastric epithelial cells in tissue culture.
Prostaglandins (PGs) protect gastric mucosa against damage produced by acetylsalicylic acid (ASA). Whether this effect of… 
1981
1981
Gastric alkaline response to mucosa-damaging agents: effect of 16,16-dimethyl prostaglandin E2.
We investigated the effects of luminal application of graded concentrations of conventional mucosal barrier breakers such as… 
Highly Cited
1981
Highly Cited
1981
Gastric gel mucus thickness: effect of distention, 16,16-dimethyl prostaglandin e2, and carbenoxolone.
Highly Cited
1978
Highly Cited
1978
Stimulation of mucus and nonparietal cell secretion by the E2 prostaglandins
The effects of prostaglandin E2 (PGE2), 15-methyl prostaglandin E2 (15M), and 16,16-dimethyl prostaglandin E2 (16DM) on gastric… 
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