13-hydroxyoctadecadienoic acid
National Institutes of Health
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The transient receptor potential vanilloid 1 (TRPV1) channel is the principal detector of noxious heat in the peripheral nervous…
The increased breast cancer risk in female night shift workers has been postulated to result from the suppression of pineal…
Both physiological and pharmacological levels of the pineal hormone melatonin exhibit substantial anticancer activity in tissue…
Melatonin, as a new member of an expanding group of regulatory factors that control cell proliferation and loss, is the only…
In the skin epidermis, the metabolism of polyunsaturated fatty acids (PUFAs) is highly active. Dietary deficiency of linoleic…
Reversal of essential fatty acid deficiency (EFA) induced epidermal hyperproliferation was recently suggested to require linoleic…
We have previously reported that endothelial cells synthesize a cytosol-associated, lipoxygenase-derived metabolite, LOX, which…