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10,11-methylenedioxycamptothecin

Known as: MDCPT cpd 
 
National Institutes of Health

Papers overview

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2014
2014
This study designs an alternative transdermal delivery system for 10,11-methylenedioxycamptothecin(MD-CPT) to inhibit keloid… Expand
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2004
2004
Camptothecin (CPT) analogs that form more stable ternary complexes with DNA and topoisomerase I (termed cleavable complexes) show… Expand
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2001
2001
UCN-01 is a hydroxylated derivative of staurosporine and a potent protein kinase C (PKC) inhibitor. Interest in the potential… Expand
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1996
1996
20(S)-Camptothecin (CPT), a topoisomerase I inhibitor specifically toxic toward S-phase cells, was tested topically for its… Expand
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1995
1995
Camptothecins belong to a group of anticancer agents with a specific mechanism of action: stabilization and trapping of… Expand
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1993
1993
The cytotoxic alkaloid camptothecin (CPT) and several of its analogues, including the clinically relevant topotecan (TPT… Expand
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1991
1991
Previous studies in rapidly proliferating rodent cells have suggested that the lethal effect of the DNA topoisomerase I inhibitor… Expand
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1990
1990
We had previously shown that 10,11-methylenedioxy-20-(RS)-camptothecin (MDO-CPT) is a more potent inhibitor of purified DNA… Expand
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