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Camptothecin
Known as:
camptothecins
, 21, 22-secocamptothecin-21-oic acid lactone
, 20(S)-Camptothecine
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An alkaloid isolated from the Chinese tree Camptotheca acuminata, with antineoplastic activity. During the S phase of the cell cycle, camptothecin…
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National Institutes of Health
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Related topics
Related topics
49 relations
Narrower (39)
10-hydroxycamptothecin
10-methoxy-9-nitrocamptothecin
11-hydroxycamptothecin
12-nitrocamptothecin
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Broader (2)
Alkaloids
Antineoplastic Agents, Phytogenic
Camptothecin Sodium
In Blood
Mureletecan
NCIt Antineoplastic Agent Terminology
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Influence of inorganic microelements on the production of camptothecin with suspension cultures of Camptotheca acuminata
Xue-Wu Pan
,
Ya-Ya Shi
,
Xin Liu
,
Xiang Gao
,
Ying-Tang Lu
Plant growth regulation (Print)
2004
Corpus ID: 44012207
The effects of eight microelements (I−, BO33−, MoO42−, Co2+, Cu2+, Mn2+, Fe2+, Zn2+) on the biosynthesis of camptothecin and the…
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1999
1999
QUANTITATION OF CAMPTOTHECIN IN NOTHAPODYTES FOETIDA
S. Puri
,
G. Handa
,
+4 authors
S. Sharma
1999
Corpus ID: 99583028
Camptothecin (1 ), a naturally occurring compound first isolated from Camptotheca acuminta 1, is an alkaloid endowed with…
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1998
1998
Characterization of cell growth and camptothecin production in cell cultures of Camptotheca acuminata
Hoon-Song Seung
,
S. Byun
1998
Corpus ID: 88148078
Studies were made to elucidate the cell growth and the production of camptothecin and its derivatives in cell cultures of…
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1997
1997
Down-regulation of topoisomerase II by camptothecin does not prevent additive activity of the topoisomerase II inhibitor etoposide in vitro
M. Stahl
,
S. Kasimir-Bauer
,
A. Harstrick
Anti-Cancer Drugs
1997
Corpus ID: 46204788
Topoisomerases (Topo) I and II are cellular enzymes that catalyze the relaxation of topologically strained DNA and that are…
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1988
1988
Clinical trial and experimental study on treating psoriasis with camptothecine.
X. Lin
,
T.-A. Huang
,
C.-M. Yang
,
C.-X. Tu
,
G.-L. Yang
Chinese Medical Journal
1988
Corpus ID: 28484085
1977
1977
Effect of camptothecin and adriamycin on bleomycin-induced tritiated thymidine triphosphate incorporation in a rat nuclear system.
George P. Sartiano
,
Mona L. Coetzee
,
Katherine A. Klein
,
Peter Ove
Journal of the National Cancer Institute
1977
Corpus ID: 46707431
We investigated the effect of camptothecin and adriamycin on [3H]TTP incorporation and bleomycin-stimulated [3H]TTP incorporation…
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1975
1975
Analogs of camptothecin.
James A. Bristol
,
D. Comins
,
+5 authors
S. Horwitz
Journal of Medicinal Chemistry
1975
Corpus ID: 31513118
Several compounds having portions of the camptothecin ring system were prepared. These compounds were screened against L1210…
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1975
1975
Action of Cis-dichlorodiammineplatinum(II) (NSC-119875) at ehe cellular level.
B. Drewinko
,
J. Gottlieb
Cancer chemotherapy reports
1975
Corpus ID: 28876811
Asynchronous human lymphoma cells treated for 1 hour with increasing concentrations of cis-dichlorodiammineplatinum(II) revealed…
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1975
1975
Effect of topical use of camptothecine-dimethyl sulfoxide solution in psoriasis.
C. Chiao
,
H. Li
Chinese Medical Journal
1975
Corpus ID: 34506067
1972
1972
Ultrastructural changes inducible with the plant alkaloid camptothecin.
Louis Recher
,
Hilary Chan
,
L. Briggs
,
Nikko T. Parry
Cancer Research
1972
Corpus ID: 5247066
The fine structural effects of camptothecin, a plant alkaloid with known antitumor activity, have been examined in ME-180 tissue…
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