Camptothecin Sodium

Known as: Camptothecin Sodium Salt, Camptothecin, sodium salt, Sodium camptothecin 
The sodium salt of camptothecin, an alkaloid isolated from the Chinese tree Camptotheca acuminata, with antineoplastic activity. During the S phase… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
To prepare a water-insoluble camptothecin (CPT) delivery carrier, hydrophobically modified glycol chitosan (HGC) nanoparticles… (More)
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Highly Cited
2004
Highly Cited
2004
We have shown previously that the camptothecin analogue topotecan (TPT), a topoisomerase I (Top 1) poison, inhibits hypoxia… (More)
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Highly Cited
2004
Highly Cited
2004
Human topoisomerase I relaxes superhelical tension associated with DNA replication, transcription and recombination by reversibly… (More)
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Highly Cited
1997
Highly Cited
1997
We have reported previously that a canalicular multispecific organic anion transporter (cMOAT) is responsible for the biliary… (More)
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Highly Cited
1996
Highly Cited
1996
Camptothecin is an S-phase-specific anticancer agent that inhibits the activity of the enzyme DNA topoisomerase-I (topo-I… (More)
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Highly Cited
1994
Highly Cited
1994
The intrinsic fluorescent emissions from the lactone and carboxylate forms of camptothecin have been exploited in order to… (More)
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Highly Cited
1993
Highly Cited
1993
The extreme S-phase-specific cytotoxicity of camptothecin has been shown to involve active DNA replication. To investigate the… (More)
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Highly Cited
1992
Highly Cited
1992
Topotecan (TPT, 9-dimethylaminomethyl-10-hydroxycamptothecin) is the first topoisomerase I-directed cytotoxic agent to enter… (More)
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Highly Cited
1990
Highly Cited
1990
A new water-soluble derivative of camptothecin, 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11), did… (More)
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