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zotepine

Known as: 2-((8-Chlorodibenzo(b,f)thiepin-10-yl)oxy)-N,N-dimethylethanamine, 2-chloro-11-(2-dimethylaminoethoxy)dibenzo(b,f)thiepine 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antipsychotic AgentsDibenzothiepins

Narrower (1)

Nipolept

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
QTc prolongation and antipsychotic medications in a sample of 1017 patients with schizophrenia
Review
2009
Review
2009
A meta-analysis of head-to-head comparisons of second-generation antipsychotics in the treatment of schizophrenia.
OBJECTIVE Whether there are differences in efficacy among second-generation antipsychotics in the treatment of schizophrenia is a… 
Highly Cited
2006
Highly Cited
2006
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.
Review
2000
Review
2000
Atypical antipsychotics and weightgain — a systematic review
Objective: To review systematically data relating to weight changes with atypical antipsychotics. 
Highly Cited
1999
Highly Cited
1999
Pharmacological profile of neuroleptics at human monoamine transporters.
Highly Cited
1996
Highly Cited
1996
A comparison of an atypical and typical antipsychotic, zotepine versus haloperidol in patients with acute exacerbation of schizophrenia: a parallel-group double-blind trial.
The atypical antipsychotic zotepine was compared to haloperidol in 126 patients suffering from acute exacerbation of… 
Highly Cited
1994
Highly Cited
1994
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
The authors examined the affinities of 36 typical and atypical antipsychotic agents for the cloned rat 5-hydroxytryptamine-6 (5… 
Highly Cited
1992
Highly Cited
1992
Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells.
We determined the affinity and selectivity of binding for 24 compounds: nine antimuscarinics (including some antiparkinson drugs… 
Highly Cited
1992
Highly Cited
1992
Zotepine in the treatment of schizophrenic patients with prevailingly negative symptoms. A double‐blind trial vs. haloperidol
&NA; Zotepine, a neuroleptic agent with additional 5‐HT2 blocking properties, was compared with haloperidol in the treatment of… 
Highly Cited
1987
Highly Cited
1987
Zotepine in the Treatment of Negative Symptoms in Chronic Schizophrenia
Zotepine is a new tricyclic neuroleptic with a pharmacological profile comparable to substances like Thioridazine and… 
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