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zopolrestat
Known as:
3,4-Dihydro-4-oxo-3-((5-(trifluoromethyl)-2-benzothiazolyl)methyl)-1-phthalazineacetic Acid
, 3,4-dihydro-4-oxo-3-((5-(trifluoromethyl)-2-benzothiazolyl)methyl)-1-phthalazine-acetic acid
National Institutes of Health
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Related topics
Related topics
4 relations
Broader (4)
Benzothiazoles
Enzyme Inhibitors
Hypoglycemic Agents
Phthalazines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Chapterr 5 EFFECTSS OF INHIBITION OF THE POLYOL PATHWAY DURING CHRONICC PERITONEAL EXPOSURE TO A DIALYSIS SOLUTION
R. Westrhenen
,
J. Aten
,
M. Aberra
,
C. Dragt
,
G. Deira
2017
Corpus ID: 31816505
T I N T R O D U C T I ON N Peritoneall dialysis with glucose and lactate containing dialysis solutions stimulates peritoneal…
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2015
2015
PP.33.22: ALDOSE REDUCTASE INHIBITORS, ZOPOLRESTAT AND FERULIC ACID, ALLEVIATE METABOLIC SYNDROME EFFECT ON ENDOTHELIAL DEPENDENT RELAXATION
H. El-Bassossy
,
D. Badawy
,
Ahmed Fahmy
2015
Corpus ID: 202808469
Objective: We have previously shown that aldose reductase (AR) inhibition, alleviate hypertension in diabetes. Here, we…
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2011
2011
Induced fit binding of aldose reductase inhibitors to AKR1B10
Anup D. Shah
,
R. Shinde
,
Pavan Kare
,
V. Hymavathi
,
Swapnil Chavan
,
M. Elizabeth Sobhia
Medicinal Chemistry Research
2011
Corpus ID: 253645441
AKR1B10 is a recently identified NADP+ dependent aldo–keto reductase. It is strongly over expressed in lung and hepatic…
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1999
1999
Effect of high galactose concentrations and zopolrestat on intracellular sodium and potassium of lens epithelial cells
A. Mears
,
E. Cruz
,
F. Diecke
1999
Corpus ID: 89038052
1995
1995
PHARMACOKINETICS IN NON‐INSULIN‐DEPENDENT DIABETICS OF THE ALDOSE REDUCTASE INHIBITOR, ZOPOLRESTAT
Philip B. Inskecp
,
Anne ii. Reed
,
A. Connolly
,
K. Wilner
,
R. Vargas
,
F. Mcmahon
American Journal of Therapeutics
1995
Corpus ID: 35619566
The pharmacokinetics of zopolrestat have been examined in non-insulin-dcpendent diabetic patients after oral administration of a…
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