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zonisamide

Known as: Zonisamida, 1,2-benzisoxazole-3-methanesulfonamide, 3-sulfamoylmethyl-1,2-benzisoxazole 
A sulfonamide derivative with an anticonvulsant property. The exact mechanism of action remains to be elucidated. Zonisamide appears to block sodium… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (3)

AD 810CI 912Zonegran

Broader (3)

AnticonvulsantsAntioxidantsIsoxazoles
Antiepileptic AgentsDrug AllergyEpilepsies, PartialEpilepsy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.
Highly Cited
2007
Highly Cited
2007
Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study.
OBJECTIVE Zonisamide and bupropion have been investigated for weight reduction in obese adults. We conducted a preliminary study… 
2007
2007
Levetiracetam monotherapy in newly diagnosed cryptogenic West syndrome.
2007
2007
Adjunctive zonisamide for treatment refractory anxiety
The aim of the study was to assess the use of a novel anticonvulsant, zonisamide, in patients with treatment refractory anxiety… 
Review
2006
Review
2006
New generation anticonvulsants for the treatment of epilepsy in children
SummaryIn the last 12 years, 10 new anticonvulsants have been approved by the U.S. Food and Drug Administration and. as a result… 
Highly Cited
2004
Highly Cited
2004
Zonisamide treatment for symptomatic infantile spasms
The authors evaluated zonisamide for symptomatic infantile spasms in 23 patients. Spasm cessation, EEG evolution, and… 
Review
2002
Review
2002
Tropical Review: Zonisamide in Pediatric Epilepsy: Review of the Japanese Experience
Zonisamide is a novel anticonvulsant that is structurally and mechanistically unique, compared with other antiepilepsy drugs… 
Highly Cited
1994
Highly Cited
1994
Inhibition by topiramate of seizures in spontaneously epileptic rats and DBA/2 mice.
1994
1994
Zonisamide‐Induced Behavior Disorder in Two Children
Summary: Zonisamide (ZNS)‐induced behavior disorders are reported in a 1‐year‐old girl and a 3‐year‐old boy. Both patients, who… 
Highly Cited
1986
Highly Cited
1986
Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy.
Zonisamide (CI-912) is an experimental antiepileptic drug. Since this drug is to be evaluated initially as an add-on medication… 
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