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zonisamide
Known as:
Zonisamida
, 1,2-benzisoxazole-3-methanesulfonamide
, 3-sulfamoylmethyl-1,2-benzisoxazole
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A sulfonamide derivative with an anticonvulsant property. The exact mechanism of action remains to be elucidated. Zonisamide appears to block sodium…
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National Institutes of Health
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Related topics
Related topics
13 relations
Narrower (3)
AD 810
CI 912
Zonegran
Broader (3)
Anticonvulsants
Antioxidants
Isoxazoles
Antiepileptic Agents
Drug Allergy
Epilepsies, Partial
Epilepsy
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.
D. Vullo
,
S. del Prete
,
+5 authors
C. Capasso
Bioorganic & Medicinal Chemistry Letters
2014
Corpus ID: 206258576
Highly Cited
2007
Highly Cited
2007
Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study.
K. Gadde
,
Gretchen M. Yonish
,
M. Foust
,
H. Ryan Wagner
Journal of Clinical Psychiatry
2007
Corpus ID: 27651690
OBJECTIVE Zonisamide and bupropion have been investigated for weight reduction in obese adults. We conducted a preliminary study…
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2007
2007
Levetiracetam monotherapy in newly diagnosed cryptogenic West syndrome.
H. Gümüş
,
S. Kumandas
,
H. Per
Pediatric Neurology
2007
Corpus ID: 23936124
2007
2007
Adjunctive zonisamide for treatment refractory anxiety
G. Kinrys
,
D. Vasconcelos E Sa
,
F. Nery
International journal of clinical practice
2007
Corpus ID: 31006041
The aim of the study was to assess the use of a novel anticonvulsant, zonisamide, in patients with treatment refractory anxiety…
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Review
2006
Review
2006
New generation anticonvulsants for the treatment of epilepsy in children
E. Donner
,
O. Snead
NeuroRx
2006
Corpus ID: 8281513
SummaryIn the last 12 years, 10 new anticonvulsants have been approved by the U.S. Food and Drug Administration and. as a result…
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Highly Cited
2004
Highly Cited
2004
Zonisamide treatment for symptomatic infantile spasms
T. Lotze
,
A. Wilfong
Neurology
2004
Corpus ID: 8642571
The authors evaluated zonisamide for symptomatic infantile spasms in 23 patients. Spasm cessation, EEG evolution, and…
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Review
2002
Review
2002
Tropical Review: Zonisamide in Pediatric Epilepsy: Review of the Japanese Experience
T. Glauser
,
J. Pellock
Journal of Child Neurology
2002
Corpus ID: 45395290
Zonisamide is a novel anticonvulsant that is structurally and mechanistically unique, compared with other antiepilepsy drugs…
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Highly Cited
1994
Highly Cited
1994
Inhibition by topiramate of seizures in spontaneously epileptic rats and DBA/2 mice.
J. Nakamura
,
S. Tamura
,
+5 authors
M. Sasa
European Journal of Pharmacology
1994
Corpus ID: 4605749
1994
1994
Zonisamide‐Induced Behavior Disorder in Two Children
S. Kimura
Epilepsia
1994
Corpus ID: 26063313
Summary: Zonisamide (ZNS)‐induced behavior disorders are reported in a 1‐year‐old girl and a 3‐year‐old boy. Both patients, who…
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Highly Cited
1986
Highly Cited
1986
Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy.
L. Ojemann
,
R. Shastri
,
+4 authors
R. Buchanan
Therapeutic Drug Monitoring
1986
Corpus ID: 28341228
Zonisamide (CI-912) is an experimental antiepileptic drug. Since this drug is to be evaluated initially as an add-on medication…
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