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zonisamide

Known as: Zonisamida, 1,2-benzisoxazole-3-methanesulfonamide, 3-sulfamoylmethyl-1,2-benzisoxazole 
A sulfonamide derivative with an anticonvulsant property. The exact mechanism of action remains to be elucidated. Zonisamide appears to block sodium… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (3)

AD 810CI 912Zonegran

Broader (3)

AnticonvulsantsAntioxidantsIsoxazoles
Antiepileptic AgentsDrug AllergyEpilepsies, PartialEpilepsy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.
Review
2010
Review
2010
Daily dose of dopaminergic medications in Parkinson disease: Clinical correlates and a posteriori equation
Objectives: To survey daily doses of dopaminergic medications and to draw a posteriori equation of the dose in relation to the… 
Highly Cited
2007
Highly Cited
2007
Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study.
OBJECTIVE Zonisamide and bupropion have been investigated for weight reduction in obese adults. We conducted a preliminary study… 
2007
2007
A novel high sensitivity HPLC assay for topiramate, using 4-chloro-7-nitrobenzofurazan as pre-column fluorescence derivatizing agent.
2007
2007
Levetiracetam monotherapy in newly diagnosed cryptogenic West syndrome.
Review
2004
Review
2004
Novel therapeutic effects of the anti-convulsant, zonisamide, on Parkinson's disease.
We found that zonisamide (ZNS) has beneficial effects on Parkinson's disease (PD). ZNS is originally synthesized in Japan and has… 
Highly Cited
2004
Highly Cited
2004
Zonisamide treatment for symptomatic infantile spasms
The authors evaluated zonisamide for symptomatic infantile spasms in 23 patients. Spasm cessation, EEG evolution, and… 
Review
2002
Review
2002
Tropical Review: Zonisamide in Pediatric Epilepsy: Review of the Japanese Experience
Zonisamide is a novel anticonvulsant that is structurally and mechanistically unique, compared with other antiepilepsy drugs… 
Highly Cited
1994
Highly Cited
1994
Inhibition by topiramate of seizures in spontaneously epileptic rats and DBA/2 mice.
Highly Cited
1986
Highly Cited
1986
Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy.
Zonisamide (CI-912) is an experimental antiepileptic drug. Since this drug is to be evaluated initially as an add-on medication… 
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