zonisamide

Known as: Zonisamida, 1,2-benzisoxazole-3-methanesulfonamide, 3-sulfamoylmethyl-1,2-benzisoxazole 
A sulfonamide derivative with an anticonvulsant property. The exact mechanism of action remains to be elucidated. Zonisamide appears to block sodium… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
02040608019792017

Papers overview

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2010
2010
Zonisamide is widely used as an antiepileptic drug. Two studies published recently in Experimental Neurology focus on the drug's… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To evaluate the efficacy, safety and tolerability of daily doses of 25, 50, and 100 mg of zonisamide (ZNS) administered… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND In response to the increase in obesity, pharmacologic treatments for weight loss have become more numerous and more… (More)
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Highly Cited
2003
Highly Cited
2003
CONTEXT Zonisamide is a marketed antiepileptic drug that has serotonergic and dopaminergic activity in addition to blockade of… (More)
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2001
2001
Zonisamide (ZNS) is a generally well tolerated anticonvulsant that has beneficial effects on Parkinson's disease (PD). ZNS (300… (More)
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1997
1997
PURPOSE We determined the short-term efficacy of zonisamide (ZNS) monotherapy in newly diagnosed patients with infantile spasms… (More)
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1996
1996
We investigated the effects of zonisamide, a new antiepileptic drug, on voltage-dependent T-type calcium current (ICa) in… (More)
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1995
1995
Effects of zonisamide (ZNS) on extracellular dopamine (DA), its precursor 3,4-dihydroxyphenylalanine (DOPA), its metabolites 3,4… (More)
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Highly Cited
1992
Highly Cited
1992
We investigated the effect of zonisamide, a new antiepileptic drug, on voltage-dependent Ca2+ currents in cultured neurons of rat… (More)
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1987
1987
In voltage-clamped Myxicola giant axons Zonisamide (1,2-benzisoxazole-3-methanesulfonamide) caused a hyperpolarizing shift in the… (More)
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