ziconotide

Known as: omega-conotoxin M VIIA, omega-conopeptide MVIIA, ziconotide [Chemical/Ingredient] 
A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Safety and efficacy data from a study of slow intrathecal (IT) ziconotide titration for the management of severe chronic pain are… (More)
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Highly Cited
2006
Highly Cited
2006
Objective.  The safety and efficacy of intrathecal (IT) ziconotide was studied in a randomized, double-blind, placebo-controlled… (More)
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Highly Cited
2005
Highly Cited
2005
Although nitric oxide (NO) has grown into a key signaling molecule in plants during the last few years, less is known about how… (More)
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Review
2004
Review
2004
Ziconotide (PRIALT) is a neuroactive peptide in the final stages of clinical development as a novel non-opioid treatment for… (More)
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Highly Cited
2002
Highly Cited
2002
We recently introduced a method (Griffin, B. A.; Adams, S. R.; Tsien, R. Y. Science 1998, 281, 269-272 and Griffin, B. A.; Adams… (More)
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Highly Cited
2002
Highly Cited
2002
The Mre11 complex (Mre11–Rad50–Nbs1) is central to chromosomal maintenance and functions in homologous recombination, telomere… (More)
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Highly Cited
1998
Highly Cited
1998
Tumor necrosis factor-alpha (TNF-alpha) is a major mediator of both acute and chronic inflammatory responses in many diseases… (More)
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Highly Cited
1990
Highly Cited
1990
THE activity of the rat insulin I gene enhancer is mainly dependent on two cis-acting protein-binding domains1–3. Here we report… (More)
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Highly Cited
1989
Highly Cited
1989
Association of oncogenic ras proteins with cellular membranes appears to be a crucial step in transformation, ras is synthesized… (More)
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Highly Cited
1982
Highly Cited
1982
Stepwise modification of a conformationally stabilised analogue of the fragment of somatostatin which had been thought to be… (More)
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