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zanolimumab

Known as: Anti-CD4 Monoclonal Antibody HuMax, HuMax-CD4 
A human IgG1k monoclonal antibody against the CD4 receptor on T-lymphocytes, with potential antineoplastic and immunosuppressing activities… Expand
National Institutes of Health

Papers overview

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2019
2019
BackgroundHuMax-IL8 (now known as BMS-986253) is a novel, fully human monoclonal antibody that inhibits interleukin-8 (IL-8), a… Expand
2017
2017
The complex signaling networks of the tumor microenvironment that facilitate tumor growth and progression toward metastatic… Expand
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Review
2016
Review
2016
Cutaneous T-cell lymphomas (CTCLs) are non-Hodgkin lymphomas that predominantly affect older patients. Onset of cutaneous… Expand
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Highly Cited
2010
Highly Cited
2010
The efficacy and safety of zanolimumab (HuMax‐CD4) in patients with relapsed or refractory peripheral T Cell lymphoma (PTCL) was… Expand
Review
2008
Review
2008
Monoclonal antibodies represent a major and increasingly important category of biotechnology products for the treatment of human… Expand
Highly Cited
2007
Highly Cited
2007
The efficacy and safety of zanolimumab in patients with refractory cutaneous T-cell lymphoma (CTCL) have been assessed in two… Expand
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2007
2007
Combination chemotherapy has been the basis of treatment for peripheral T-cell lymphoma (PTCL) for many years, but relapses are… Expand
Highly Cited
2005
Highly Cited
2005
OBJECTIVE Interleukin-15 (IL-15) is a proinflammatory, innate response cytokine that mediates pleiotropic effector function in… Expand
2005
2005
A patient with a CD4+ refractory peripheral T-cell lymphoma (PTL), subtype angioimmunoblastic T-cell lymphoma (AILD), was treated… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Psoriasis is characterized by infiltration with mononuclear cells. Especially activated memory CD4+ T cells are… Expand
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