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zamifenacin

Known as: (3-diphenylmethoxy-1-(3,4)-methylenedioxyphenethyl)piperidine, (R)-3-(Diphenylmethoxy)-1-(3,4-(methylenedioxy)phenethyl)piperidine 
National Institutes of Health

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Related topics

2 relations

Broader (2)

DioxolesPiperidines

Papers overview

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2002
2002
Muscarinic receptors in isolated urinary bladder smooth muscle from different mouse strains
The pharmacological characteristics of muscarinic receptors in male and female mouse urinary bladder smooth muscle from different… 
Review
2001
Review
2001
Drug Treatment Options for Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a functional gut disorder the diagnosis of which is based on clinical symptoms as set forth by… 
2000
2000
The role of Ca2+ stores in the muscarinic inhibition of the K+ current IK(SO) in neonatal rat cerebellar granule cells
1 Cerebellar granule neurons (CGNs) possess a standing outward potassium current (IK(SO)) which shares many similarities with… 
Review
2000
Review
2000
New developments in the treatment of irritable bowel syndrome.
The irritable bowel syndrome (IBS) is one of the most common gastrointestinal conditions encountered by general practitioners… 
1999
1999
Characterization of the muscarinic receptor in isolated uterus of sham operated and ovariectomized rats
The pharmacological characteristics of muscarinic receptors in rat isolated uterus were studied in ovariectomized (ov.) and sham… 
1998
1998
In vitro toxicity of zamifenacin (UK-76,654) and metabolites in primary hepatocyte cultures.
1. We compared the sensitivities of primary hepatocytes from rat, dog and monkey to zamifenacin and two major metabolites, the… 
1998
1998
Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea‐pig isolated uterus
In many smooth muscle tissues a minor M3‐muscarinic acetylcholine (mACh) receptor population mediates contraction, despite the… 
1997
1997
Contraction of guinea-pig gallbladder: muscarinic M3 or M4 receptors?
1996
1996
Pharmacokinetics and metabolism of zamifenacin in mouse, rat, dog and man.
1. Zamifenacin was rapidly metabolized in vitro by liver microsomes from rat, dog, and man. 2. Zamifenacin exhibited extensive… 
1995
1995
Pre-clinical and clinical pharmacology of selective muscarinic M3 receptor antagonists.
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