yersiniabactin
National Institutes of Health
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Many bacteria produce siderophores for sequestration of growth-essential iron. Analysis of the Salinispora genomes suggests that…
Microbes employ several catalytic strategies to transform conformationally flexible peptide chains into rigidified scaffolds that…
The shikimate biosynthetic pathway is utilized in algae, higher plants, bacteria, fungi and apicomplexan parasites; it involves…
For interrogation of enzyme-bound intermediates in nonribosomal peptide synthetases (NRPSs), mass spectrometry is used to read…
Complex arrays of thioester bound intermediates are present on 100-700 kDa enzymes during the biogenesis of diverse types of…
ABSTRACT One requirement for the pathogenesis of Yersinia pestis, the causative agent of bubonic plague, is the yersiniabactin…
The HMWP2 subunit of yersiniabactin (Ybt) synthetase, a 230 kDa nonribosomal peptide synthetase (NRPS) making the N-terminus of…
ABSTRACT In Yersinia pestis, the causative agent of plague, two inorganic iron transport systems have been partially…
ABSTRACT One prerequisite for the virulence of Yersinia pestis, causative agent of bubonic plague, is the yersiniabactin (Ybt…
Yersinia enterocolitica strains of serotype O8 but not strains of other human pathogenic serotypes (e.g., O3 or O9) are able to…