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wrenchnolol

National Institutes of Health

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AdamantaneIndoles

Papers overview

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2009
2009
Wrenchnolol derivative optimized for gene activation in cells.
Naturally occurring transcription factors usually have two independent domains, a DNA-binding domain and an activation domain. In… 
2006
2006
Synthesis of synthetic small molecule transcription factors (STF).
External control of gene expression by small synthetic molecules represents a challenge in chemistry. Here we discuss the… 
2006
2006
Isolation of the novel bioactive compounds from Okinawan sponges and development of the jolkinolide D pharmacophore and wrenchnolol that interact with biomolecules
Highly Cited
2004
Highly Cited
2004
Small molecule transcription factor mimic.
Regulation of gene expression by transcription factors touches many aspects of eukaryotic biology, and its systematic, external… 
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