vildagliptin

Known as: (2S)-(((3-hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile 
A cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiety… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
AIM To show that vildagliptin added to metformin is non-inferior to glimepiride in reducing HbA1c levels from baseline over 2… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Highly Cited
2009
Highly Cited
2009
AIM To examine the efficacy and safety of vildagliptin vs. glimepiride as add-on therapy to metformin in patients with type 2… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
OBJECTIVE We sought to evaluate the efficacy and safety of vildagliptin, a new dipeptidyl peptidase-4 inhibitor, added to… (More)
  • table 1
  • figure 1
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Type 2 diabetes is difficult to manage in patients with a long history of disease requiring insulin therapy. Moreover, addition… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
UNLABELLED This 24-week, double-blind, randomized, multicenter, placebo-controlled, parallel-group study performed in 354 drug-na… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
OBJECTIVE To compare the efficacy and tolerability of vildagliptin and rosiglitazone during a 24-week treatment in drug-naïve… (More)
  • figure 1
  • table 1
  • figure 2
Is this relevant?
Review
2006
Review
2006
Glucagon-like peptide 1 (GLP-1) is a gut-derived incretin hormone that stimulates insulin and suppresses glucagon secretion… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
We assessed the effects of vildagliptin, a novel dipeptidyl peptidase IV inhibitor, on postprandial lipid and lipoprotein… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
OBJECTIVE To examine the effects of dipeptidyl peptidase-IV (DPP-4) inhibition on meal-related beta-cell function and insulin… (More)
  • table 1
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2005
Highly Cited
2005
AIMS/HYPOTHESIS The dipeptidyl peptidase IV inhibitor, vildagliptin, increases levels of intact glucagon-like peptide-1 (GLP-1… (More)
Is this relevant?