vernolepin

Sleeping sickness or human African trypanosomiasis (HAT) is a neglected tropical disease (NTD) threatening millions of peoples… (More)

The aerial parts of VERNONIA GLABRA afforded in addition to vernolepin, vernodalin and vernomenin, four further sesquiterpene… (More)

The sesquiterpene lactone antineoplastic vernolepin acutely depletes murine tumor cell glutathione (GSH), and lyses the cells by… (More)

Glutathione, as the chief nonprotein intracellular sulfhydryl, affects the efficacy and interactions of a variety of… (More)

Vernolepin, a sesquiterpene lactone, was isolated from the dried fruit of Vernonia amygdalina Del. The different steps used… (More)

GSH plays an important role in cellular defense against a wide variety of toxic electrophiles via the formation of thioether… (More)

Rats bearing the Walker 256 intramuscular carcinosarcoma were treated intraperitoneally with tritium-labeled vernolepin or with… (More)

 

The plant-derived tumor inhibitors taxodone, taxodione, vernolepin, eupacunin, and euparotin acetate each inhibit the sulfhydryl… (More)

Vernolepin (5 to 50 micrograms per milliliter), a novel sesquiterpenoid dilactone obtained from Vernonia hymenolepis, inhibits… (More)