Author pages are created from data sourced from our academic publisher partnerships and public sources.
Share This Author
Three new triterpenes from Nerium oleander and biological activity of the isolated compounds.
The anti-inflammatory activity of the seven isolated compounds and methyl esters of ursolic acid and oleanoic acid in vitro was examined on the basis of inhibitory activity against the induction of the intercellular adhesion molecule-1 (ICAM-1).
Bioactive lignans from Peperomia duclouxii.
Six new lignans (1-6), along with 14 known compounds, were obtained from Peperomia duclouxii and showed anti-inflammatory activity using an ICAM-1 assay (induction of the intercellular adhesion molecule-1), stimulated by IL-1alpha and TNF-alpha.
Dibenzylbutyrolactone and dibenzylbutanediol lignans from Peperomia duclouxii.
Nine new lignans (1-9) were obtained from an ethyl acetate extract of the whole plants of Peperomia duclouxii, and the absolute structures were elucidated as 2S,3S from their optical rotations and by chemical transformations.
Guaianolides as immunomodulators. Synthesis and biological activities of dehydrocostus lactone, mokko lactone, eremanthin, and their derivatives.
It was observed during the present study that the guaianolides possessing an alpha-methylene gamma-lactone moiety exhibited significant inhibitory activity toward the killing function of CTL and the induction of ICAM-1.
Bioactive triterpene saponins from the roots of Phytolacca americana.
The MDR-reversal activity of 1-12 was evaluated on the basis of the amount of calcein accumulated in MDR human ovarian cancer 2780 AD cells in the presence of each compound, and the most effective compound was 8 (155% of control at 25 microg/mL).
Bioactive secolignans from Peperomia dindygulensis.
Thirteen secolignans, including eight new ones (1-8), were isolated from the EtOAc extract of Peperomia dindygulensis and showed inhibitory activity on induction of the intercellular adhesion molecule-1 (ICAM-1).
Bioactive polyketides from Peperomia duclouxii.
Four new compounds (1-4) were isolated along with 16 known compounds from whole plants of Peperomia duclouxii, showing moderate to weak inhibitory activity on the induction of the intercellular adhesion molecule-1 (ICAM-1) in the presence of IL-1alpha or TNF-alpha.
Bioactive guaianolides from siyekucai (Ixeris chinensis).
Two new guaianolides, named chinensiolides D (5) and E (6), were isolated from Ixeris chinensis Nakai, and their structures were determined to be…
Production of biologically active taxoids by a callus culture of Taxus cuspidata.
Taxinine NN-11 (1) is a new taxane whose structure was assigned as 5alpha,13alpha-diacetoxy-9alpha-cinnamoyloxy-4(20),11-taxadien-10beta-ol by analysis of its spectral data and exhibited significant MDR reversal activity toward 2780 AD tumor cells.
Synthetic approach to exo-endo cross-conjugated cyclohexadienones and its application to the syntheses of dehydrobrachylaenolide, isodehydrochamaecynone, and trans-isodehydrochamaecynone.
Eudesmanolides possessing an alpha-methylene gamma-lactone moiety, i.e., 1, 7, and 13, exhibited significant inhibitory activity toward the induction of the intercellular adhesion molecule-1 (ICAM-1).