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verdinexor

National Institutes of Health

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3 relations

Broader (2)

AcrylamidesHydrazines

Narrower (1)

KPT-335

Papers overview

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2019
2019
228 Verdinexor, an inhibitor of the nuclear export protein exportin-1 prevents lupus progression by limiting germinal center formation and development of autoreactive antibody secreting cells
Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by simultaneous activation of the… 
2019
2019
THU0241 LUPUS PROGRESSION IS PREVENTED BY TREATMENT WITH VERDINEXOR, AN INHIBITOR OF THE NUCLEAR EXPORT PROTEIN EXPORTIN-1, BY LIMITING GERMINAL CENTER FORMATION AND DEVELOPMENT OF AUTOREACTIVE…
Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by simultaneous activation of the… 
2014
2014
Abstract 3809: Evaluation of the novel, orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 (verdinexor) in spontaneous canine cancer: Results of phase I and phase II clinical…
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA SINE (Selective Inhibitors of Nuclear Export) block the… 
2014
2014
Elizabeth In Vivo and In Vitro Replication Nuclear Export , Reduces Influenza A Virus Verdinexor , a Novel Selective Inhibitor of
Influenza is a global health concern, causing death, morbidity, and economic losses. Chemotherapeutics that target influenza… 
2013
2013
Evaluation Of The Novel, Orally Bioavailable Selective Inhibitor Of Nuclear Export (SINE) Verdinexor (KPT-335) In Spontaneous Canine Cancer: Results Of Phase I and Phase II Clinical Trials
SINE (Selective Inhibitors of Nuclear Export) block the activity of XPO1/CRM1, 1 of 7 nuclear export proteins in cells, forcing… 
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