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KPT-335
National Institutes of Health
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verdinexor
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2014
2014
Abstract 3809: Evaluation of the novel, orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 (verdinexor) in spontaneous canine cancer: Results of phase I and phase II clinical…
C. London
,
L. F. Bernabe
,
+13 authors
S. Shacham
2014
Corpus ID: 57159030
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA SINE (Selective Inhibitors of Nuclear Export) block the…
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2014
2014
Novel Therapeutics In Renal Disease Novel inhibitors of nuclear transport cause cell cycle arrest and decrease cyst growth in ADPKD associated with decreased CDK 4 levels
Matthew Tan
,
Hiromi I. Wettersten
,
+5 authors
R. Weiss
2014
Corpus ID: 6901894
Matthew Tan, Hiromi I. Wettersten, Kristy Chu, David L. Huso, Terry Watnick, Sharon Friedlander, Yosef Landesman, and Robert H…
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2014
2014
Elizabeth In Vivo and In Vitro Replication Nuclear Export , Reduces Influenza A Virus Verdinexor , a Novel Selective Inhibitor of
Olivia Perwitasari
,
Scott K. Johnson
,
+8 authors
R. Tripp
2014
Corpus ID: 207879738
Influenza is a global health concern, causing death, morbidity, and economic losses. Chemotherapeutics that target influenza…
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2013
2013
Evaluation Of The Novel, Orally Bioavailable Selective Inhibitor Of Nuclear Export (SINE) Verdinexor (KPT-335) In Spontaneous Canine Cancer: Results Of Phase I and Phase II Clinical Trials
C. London
,
L. F. Bernabe
,
+13 authors
M. Kauffman
2013
Corpus ID: 73780461
SINE (Selective Inhibitors of Nuclear Export) block the activity of XPO1/CRM1, 1 of 7 nuclear export proteins in cells, forcing…
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2012
2012
Abstract LB-232: Preliminary results of a phase I study of the novel CRM1 inhibitors KPT-276 and KPT-335 in dogs with spontaneous cancer
C. London
,
Sandra Barnard
,
W. Kisseberth
,
L. Plamondon
,
S. Shacham
,
M. Kauffman
2012
Corpus ID: 72308139
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Introduction: KPT-276 and KPT-335 are irreversible…
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