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vegfr3 protein, human

Known as: FMS-Like Tyrosine Kinase 4, VEGF-receptor-3, FLT4 
Vascular endothelial growth factor receptor 3 (1363 aa, ~153 kDa) is encoded by the human FLT4 gene. This protein is involved in tyrosine… 
National Institutes of Health

Related topics

Related topics

39 relations
Angiogenesis PathwayAngiogenic ProcessCediranib MaleateCell Differentiation process

Broader (1)

Vascular Endothelial Growth Factor Receptor-3

Papers overview

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Highly Cited
2018
Highly Cited
2018
Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival
Angiocrine signals derived from endothelial cells are an important component of intercellular communication and have a key role… 
Highly Cited
2017
Highly Cited
2017
VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling
Rationale: Vascular endothelial growth factor (VEGF) is the main driver of angiogenesis and vascular permeability via VEGF… 
Highly Cited
2014
Highly Cited
2014
Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point
Vascular remodeling under conditions of growth or exercise, or during recovery from arterial restriction or blockage is essential… 
Highly Cited
2008
Highly Cited
2008
Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D Is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos
ABSTRACT Lymphatic vessels play an important role in the regulation of tissue fluid balance, immune responses, and fat adsorption… 
Highly Cited
2002
Highly Cited
2002
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.
BACKGROUND Vascular endothelial growth factor C (VEGF-C) stimulates tumor lymphangiogenesis (i.e., formation of lymphatic vessels… 
Review
2000
Review
2000
Regulation of angiogenesis via vascular endothelial growth factor receptors.
Endothelial cell signal transduction mechanisms involved in angiogenesis have come into focus in cancer research when it was… 
Highly Cited
2000
Highly Cited
2000
Monoclonal antibodies to vascular endothelial growth factor-D block its interactions with both VEGF receptor-2 and VEGF receptor-3.
Vascular endothelial growth factor-D (VEGF-D), the most recently discovered mammalian member of the VEGF family, is an angiogenic… 
Highly Cited
1999
Highly Cited
1999
Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors
Among the molecules important to angiogenesis and lymphangiogenesis is vascular endothelial growth factor receptor 3 (VEGFR‐3), a… 
Highly Cited
1996
Highly Cited
1996
The role of AV2 ("precoat") and coat protein in viral replication and movement in tomato leaf curl geminivirus.
We analyzed various mutants of tomato leaf curl virus-India to investigate the role of ORFs AV3, AV2, and coat protein (CP) in… 
Highly Cited
1994
Highly Cited
1994
Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors.
The FLT4, FLT1 and KDR/FLK1 genes encode structurally similar endothelial cell receptor tyrosine kinases. Recently it has been… 
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