vedolizumab

Known as: Immunoglobulin G1, anti-(human integrin LPAM-1 (lymphocyte Peyer's patch adhesion molecule 1)) (human-Mus musculus heavy chain), disulfide with human-Mus musculus kappa-chain, dimer 
A recombinant humanized immunoglobulin G1 (IgG1) monoclonal antibody directed against the human lymphocyte Peyer's patch adhesion molecule 1 (LPAM-1… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Various therapeutic advances have led to a paradigm shift in the clinical management of patients with IBD. The introduction of… (More)
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Highly Cited
2017
Highly Cited
2017
OBJECTIVE Vedolizumab is a gut-selective antibody to α4β7 integrin for the treatment of ulcerative colitis (UC) and Crohn's… (More)
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Highly Cited
2014
Highly Cited
2014
BACKGROUND & AIMS There is an increasing need for new treatments for patients with Crohn's disease (CD) in whom previous therapy… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Gut-selective blockade of lymphocyte trafficking by vedolizumab may constitute effective treatment for ulcerative… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND The efficacy of vedolizumab, an α4β7 integrin antibody, in Crohn's disease is unknown. METHODS In an integrated… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Vedolizumab is a gut-selective biologic that has shown efficacy in ulcerative colitis (UC) and Crohn's disease (CD… (More)
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Highly Cited
2012
Highly Cited
2012
Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 2: Current management Axel… (More)
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Highly Cited
2009
Highly Cited
2009
Vedolizumab is a humanized monoclonal antibody that targets the alpha(4)beta(7) integrin exclusively, and modulates inflammation… (More)
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Review
2000
Review
2000
Between 10%-28% of patients who receive the immunosuppressant cyclosporine (CsA) experience some form of neurotoxic adverse event… (More)
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Highly Cited
1982
Highly Cited
1982
The endogenous ecotropic murine leukemia virus DNA content and integration sites were characterized for 54 inbred strains and… (More)
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