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variolin B

National Institutes of Health

Papers overview

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2017
2017
Variolin B is a rare marine alkaloid that showed promising anti-cancer activity soon after its isolation. It acts as a cyclin… 
2010
2010
Chapter 1: Introduction Pictet-Spengler reaction has been extensively studied in the area of synthesis of different biologically… 
Highly Cited
2007
Highly Cited
2007
Protein kinases represent promising anticancer drug targets. We describe here the meriolins, a new family of inhibitors of cyclin… 
2006
2006
The marine alkaloid variolin B 2 and eight synthetic derivatives with different substituents at positions C-5 and C-7 have been… 
2005
2005
The total synthesis of the marine alkaloid variolin B has been achieved in 8 steps and 17% overall yield, starting from… 
2003
2003
Two alternative synthetic routes have been developed for the preparation of variolin B and deoxyvariolin B. The strategy is based… 
2003
2003
A total synthesis of the marine alkaloid variolin B has been completed in 13 steps in an overall yield of 6.5% from 3-formyl-4… 
2001