variolin B

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
01220032017

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2017
2017
Variolin B is a rare marine alkaloid that showed promising anti-cancer activity soon after its isolation. It acts as a cyclin… (More)
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2008
2008
A new total synthesis of the alkaloid variolin B is achieved by a selective and sequential palladium-mediated functionalization… (More)
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2008
2008
We report the synthesis and biological characterization of 3-(pyrimidin-4-yl)-7-azaindoles (meriolins), a chemical hybrid between… (More)
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2007
2007
Protein kinases represent promising anticancer drug targets. We describe here the meriolins, a new family of inhibitors of cyclin… (More)
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2007
2007
A new and selective palladium-catalyzed amination of the pyrido[3 0,3 0:4,5]pyrrolo[1,2-c]pyrimidine nucleus, the heterocyclic… (More)
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2006
2006
The marine alkaloid variolin B 2 and eight synthetic derivatives with different substituents at positions C-5 and C-7 have been… (More)
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2005
2005
Variolin B (VAR-B) is a natural product isolated from the sponge Kirkpatrickia variolosa, found in Antarctica. VAR-B has been… (More)
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2005
2005
The total synthesis of the marine alkaloid variolin B has been achieved in 8 steps and 17% overall yield, starting from… (More)
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2003
2003
Two alternative synthetic routes have been developed for the preparation of variolin B and deoxyvariolin B. The strategy is based… (More)
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2003
2003
A total synthesis of the marine alkaloid variolin B has been completed in 13 steps in an overall yield of 6.5% from 3-formyl-4… (More)
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