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varenicline

Known as: 6,7,8,9-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)benzazepine, 7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine (2R,3R)-2,3-dihydroxybutqanedioate, Varenicline [Chemical/Ingredient] 
A partial agonist of the nicotinic acetylcholine receptor (nAChR) subtype alpha4beta2. Nicotine stimulation of central alpha4beta2 nAChRs located at… 
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (3)

ChampixChantixvarenicline tartrate
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

Nicotinic Agonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Nicotine and ethanol cooperate to enhance ventral tegmental area AMPA receptor function via α6-containing nicotinic receptors
Review
2014
Review
2014
Role for the nicotinic cholinergic system in movement disorders; therapeutic implications.
Highly Cited
2013
Highly Cited
2013
Neuropsychiatric events in varenicline and nicotine replacement patch users in the Military Health System.
AIM To determine the rate ratio of neuropsychiatric hospitalizations in new users of varenicline compared to new users of… 
2012
2012
Use of an α3β4 nicotinic acetylcholine receptor subunit concatamer to characterize ganglionic receptor subtypes with specific subunit composition reveals species-specific pharmacologic properties
Review
2012
Review
2012
[Smokeless tobacco and cardiovascular risk].
Review
2009
Review
2009
Nicotinic receptor-based therapeutics and candidates for smoking cessation.
Review
2009
Review
2009
Varenicline-Induced Mania in a Bipolar Patient
Objective:Varenicline is a novel antismoking agent that reduces cravings and blocks pleasure of nicotine by serving as a partial… 
Highly Cited
2008
Highly Cited
2008
Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice.
Varenicline, a partial agonist for a4ss2 nicotinic acetylcholine receptors (nAChRs) and full agonist for a7 nAChRs, has been… 
Highly Cited
2006
Highly Cited
2006
Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro.
The metabolism and disposition of varenicline (7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine), a partial… 
Review
2005
Review
2005
Z.: Micromixers – a review
  • 2005
  • Corpus ID: 7146885
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