uracil-DNA glycosylase

Known as: Ura DNA Glycosidase, N-Glycosylase, Uracil, Glycosylase, Ung DNA 
An enzyme that catalyzes the HYDROLYSIS of the N-glycosidic bond between sugar phosphate backbone and URACIL residue during DNA synthesis.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
DNA methylation is a major epigenetic mechanism for gene silencing. Whereas methyltransferases mediate cytosine methylation, it… (More)
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Highly Cited
2003
Highly Cited
2003
Activation-induced cytidine deaminase (AID) is a 'master molecule' in immunoglobulin (Ig) class-switch recombination (CSR) and… (More)
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Highly Cited
2002
Highly Cited
2002
A functional immune system depends on the production of a wide range of immunoglobulin molecules. Immunoglobulin variable region… (More)
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Highly Cited
1998
Highly Cited
1998
Three high-resolution crystal structures of DNA complexes with wild-type and mutant human uracil-DNA glycosylase (UDG), coupled… (More)
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Review
1997
Review
1997
A wide range of cytotoxic and mutagenic DNA bases are removed by different DNA glycosylases, which initiate the base excision… (More)
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Highly Cited
1996
Highly Cited
1996
ANY uracil bases in DNA, a result of either misincorporation or deamination of cytosine, are removed by uracil-DNA glycosylase… (More)
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Highly Cited
1995
Highly Cited
1995
Crystal structures of the DNA repair enzyme human uracil-DNA glycosylase (UDG), combined with mutational analysis, reveal the… (More)
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Highly Cited
1991
Highly Cited
1991
We have isolated and characterized a plasmid (pChug 20.1) that contains the cDNA of a nuclear uracil DNA glycosylase (UDG) gene… (More)
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Highly Cited
1990
Highly Cited
1990
Polymerase chain reactions (PCRs) synthesize abundant amplification products. Contamination of new PCRs with trace amounts of… (More)
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Highly Cited
1987
Highly Cited
1987
Several single-base substitution mutations have been introduced into the lacZa gene in cloning vector M13mp2, at 40-60… (More)
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