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type B pancreatic cell differentiation

Known as: pancreatic B cell differentiation, pancreatic beta cell differentiation 
The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

endocrine pancreas development

Narrower (1)

type B pancreatic cell development

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Real-time observation of pancreatic beta cell differentiation from human induced pluripotent stem cells.
Directed differentiation of human pluripotent stem cells (hPSCs) into functional insulin-producing cells (IPCs) holds great… 
2018
2018
Pancreatic Beta Cell Differentiation From Human Pluripotent Stem Cells
Insulin‐expressing beta cells are crucial for the maintenance of systemic glucose homeostasis. Elucidation of the molecular and… 
Review
2015
Review
2015
Role of islet microRNAs in diabetes: which model for which question?
MicroRNAs are important regulators of gene expression. The vast majority of the cells in our body rely on hundreds of these tiny… 
2015
2015
Dynamic Proteomic Analysis of Pancreatic Mesenchyme Reveals Novel Factors That Enhance Human Embryonic Stem Cell to Pancreatic Cell Differentiation
Current approaches in human embryonic stem cell (hESC) to pancreatic beta cell differentiation have largely been based on… 
Highly Cited
2012
Highly Cited
2012
Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.
Highly Cited
2009
Highly Cited
2009
Exendin-4 Promotes Liver Cell Proliferation and Enhances the PDX-1-induced Liver to Pancreas Transdifferentiation Process*
Over the last few years, evidence has accumulated revealing the unexpected potential of committed mammalian cells to convert to a… 
2008
2008
Early loss of mammalian target of rapamycin complex 1 (mTORC1) signalling and reduction in cell size during dominant-negative suppression of hepatic nuclear factor 1-α (HNF1A) function in INS-1…
Aims/hypothesisMutations in the HNF1A (previously known as TCF1) gene encoding hepatocyte nuclear factor-1α (HNF1A) lead to the… 
Review
2007
Review
2007
Role of FoxO Proteins in Pancreatic beta Cells.
Forkhead transcription factors of the FoxO family have important roles in cellular proliferation, apoptosis, differentiation and… 
Highly Cited
2006
Highly Cited
2006
PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.
Highly Cited
1993
Highly Cited
1993
Nerve growth factor induces neuron-like differentiation of an insulin-secreting pancreatic beta cell line.
Nerve growth factor (NGF) is the best understood of a class of trophic proteins that are important for the survival of neurons… 
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