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Mutant KRAS is a druggable target for pancreatic cancer
Significance Pancreatic cancer is still one of the major challenges in clinical oncology. Mutant KRAS is a driving oncogene in the majority of human pancreatic cancer cases. We have made an effort toExpand
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Exendin-4 Promotes Liver Cell Proliferation and Enhances the PDX-1-induced Liver to Pancreas Transdifferentiation Process*
Over the last few years, evidence has accumulated revealing the unexpected potential of committed mammalian cells to convert to a different phenotype via a process called transdifferentiation orExpand
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NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
Reprogramming adult mammalian cells is an attractive approach for generating cell-based therapies for degenerative diseases, such as diabetes. Adult human liver cells exhibit a high level ofExpand
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NKX 6 . 1 Promotes PDX-1-Induced Liver to Pancreatic b-Cells Reprogramming
Reprogramming adult mammalian cells is an attractive approach for generating cell-based therapies for degenerative diseases, such as diabetes. Adult human liver cells exhibit a high level ofExpand
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