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tumor necrosis
Known as:
tumour necrosis
, necrosis tumor
, Oncolysis
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The lysis (breakdown) of cancer cells. This can be caused by chemical or physical means (for example, strong detergents or high-energy sound waves…
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National Institutes of Health
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Papers overview
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Highly Cited
2004
Highly Cited
2004
Granulomatous infectious diseases associated with tumor necrosis factor antagonists.
R. Wallis
,
M. Broder
,
J. Y. Wong
,
M. Hanson
,
D. Beenhouwer
Clinical Infectious Diseases
2004
Corpus ID: 41226022
The relationship between the use of tumor necrosis factor antagonists and onset of granulomatous infection was examined using…
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Highly Cited
2002
Highly Cited
2002
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
M. Calfon
,
Huiqing Zeng
,
+5 authors
D. Ron
Nature
2002
Corpus ID: 4319118
The unfolded protein response (UPR), caused by stress, matches the folding capacity of endoplasmic reticulum (ER) to the load of…
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Highly Cited
2001
Highly Cited
2001
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
F. Hayashi
,
Kelly D. Smith
,
+7 authors
A. Aderem
Nature
2001
Corpus ID: 4422702
The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, but…
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Highly Cited
1999
Highly Cited
1999
BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth
P. Schneider
,
F. Mackay
,
+13 authors
J. Tschopp
Journal of Experimental Medicine
1999
Corpus ID: 15412891
Members of the tumor necrosis factor (TNF) family induce pleiotropic biological responses, including cell growth, differentiation…
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Highly Cited
1993
Highly Cited
1993
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
K. Kim
,
Bing Li
,
+4 authors
N. Ferrara
Nature
1993
Corpus ID: 4322780
THE development of new blood vessels (angiogenesis) is required for many physiological processes including embryogenesis, wound…
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Review
1993
Review
1993
Tumor necrosis factor, other cytokines and disease.
K. Tracey
,
A. Cerami
Annual Review of Cell Biology
1993
Corpus ID: 45170216
INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 1 7 CYTOKINES AND EFFECTS…
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Review
1991
Review
1991
Tumor necrosis factor.
Philip E Wakefield
,
W. James
,
C. Samlaska
,
M. Meltzer
Journal of American Academy of Dermatology
1991
Corpus ID: 4818289
Highly Cited
1990
Highly Cited
1990
Elevated circulating levels of tumor necrosis factor in severe chronic heart failure.
B. Levine
,
J. Kalman
,
L. Mayer
,
H. Fillit
,
M. Packer
New England Journal of Medicine
1990
Corpus ID: 22142433
BACKGROUND AND METHODS Although cachexia often accompanies advanced heart failure, little is known about the causes of the…
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Highly Cited
1989
Highly Cited
1989
The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells.
S. Endres
,
R. Ghorbani
,
+7 authors
P. Weber
New England Journal of Medicine
1989
Corpus ID: 218653561
We examined whether the synthesis of interleukin-1 or tumor necrosis factor, two cytokines with potent inflammatory activities…
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Highly Cited
1975
Highly Cited
1975
An endotoxin-induced serum factor that causes necrosis of tumors.
E. Carswell
,
L. Old
,
R. Kassel
,
S. Green
,
N. Fiore
,
B. Williamson
Proceedings of the National Academy of Sciences…
1975
Corpus ID: 10535122
In studying "hemorrhagic necrosis" of tumors produced by endotoxin, it was found that the serum of bacillus Calmette--Guerin (BCG…
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