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tryptophan synthase activity

Known as: L-serine hydro-lyase (adding indoleglycerol-phosphate), L-tryptophan synthetase activity, indoleglycerol phosphate aldolase activity 
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. [RHEA:10535]
National Institutes of Health

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2 relations
Tryptophan Synthase

Broader (1)

tryptophan biosynthetic process

Papers overview

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2013
2013
Cane molasses as a source of precursors in the bioproduction of tryptophan by Bacillus subtilis
BACKGROUND AND OBJECTIVES The essential amino acid L-tryptophan can be produced by a condensation reaction between indole and L… Expand
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2008
2008
Production of alkaloids and differentiation in a submerged culture ofClaviceps purpurea (Fr.) Tul
The submerged culture of theClaviceps purpurea strain studied was polymorphous. In. the process of alkaloid synthesis… Expand
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1986
1986
Conformational effects of ligand binding on the beta 2 subunit of Escherichia coli tryptophan synthase analyzed with monoclonal antibodies.
Five monoclonal antibodies recognizing five different epitopes of the native beta 2 subunit of Escherichia coli tryptophan… Expand
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1985
1985
Cloning and expression of tryptophan genes from Brevibacterium lactofermentum in Escherichia coli.
A gene bank from the amino acid producer Brevibacterium lactofermentum has been prepared in Escherichia coli using pBR322 as… Expand
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1983
1983
Production L-tryptophan by Escherichia coli cells.
Whole cells of Escherichia coli B 10 having high tryptophan synthetase activity were used directly as an enzyme source to produce… Expand
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1977
1977
Derepression of E. coli trp operon on interfamilial transfer
THE P-group R factor RP4 originally isolated from Pseudomonas aeruginosa can be transferred to many Gram-negative bacteria1–3. In… Expand
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1972
1972
Physiological studies on ergot: further studies on the induction of alkaloid synthesis by tryptophan and its inhibition by phosphate.
The failure of l-leucine to stimulate ergot alkaloid production in a synthetic medium indicates that the previously observed… Expand
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1969
1969
Effect of gene dosage on tryptophan synthetase activity in Saccharomyces cerevisiae.
A direct relation between gene dosage and amount of the corresponding protein is generally assumed to exist though it has been… Expand
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1958
1958
Restoration of tryptophan synthetase activity in Escherichia coli by suppressor mutations.
 
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1953
1953
Properties of mutants of Neurospora crassa with low pyruvic carboxylase activity.
Abstract The car mutant of Neurospora shows low pyruvic carboxylase activity compared to wild type ( car + ). It is probable that… Expand
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