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tryptophan synthase activity

Known as: L-serine hydro-lyase (adding indoleglycerol-phosphate), L-tryptophan synthetase activity, indoleglycerol phosphate aldolase activity 
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. [RHEA:10535]
National Institutes of Health

Related topics

Related topics

2 relations
Tryptophan Synthase

Broader (1)

tryptophan biosynthetic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Cane molasses as a source of precursors in the bioproduction of tryptophan by Bacillus subtilis
Background and Objectives The essential amino acid L-tryptophan can be produced by a condensation reaction between indole and L… 
1986
1986
Conformational effects of ligand binding on the beta 2 subunit of Escherichia coli tryptophan synthase analyzed with monoclonal antibodies.
Five monoclonal antibodies recognizing five different epitopes of the native beta 2 subunit of Escherichia coli tryptophan… 
1985
1985
Cloning and expression of tryptophan genes from Brevibacterium lactofermentum in Escherichia coli.
1983
1983
Production L‐tryptophan by Escherichia coli cells
Whole cells of Escherichia coli B 10 having high tryptophan synthetase activity were used directly as an enzyme source to produce… 
1977
1977
Derepression of E. coli trp operon on interfamilial transfer
THE P-group R factor RP4 originally isolated from Pseudomonas aeruginosa can be transferred to many Gram-negative bacteria1–3. In… 
Highly Cited
1972
Highly Cited
1972
Physiological Studies on Ergot: Further Studies on the Induction of Alkaloid Synthesis by Tryptophan and Its Inhibition by Phosphate
The failure of l-leucine to stimulate ergot alkaloid production in a synthetic medium indicates that the previously observed… 
1969
1969
Effect of gene dosage on tryptophan synthetase activity in Saccharomyces cerevisiae.
A direct relation between gene dosage and amount of the corresponding protein is generally assumed to exist though it has been… 
1960
1960
Mediation of the Genetic Control of Protein Synthesis in Cell-free Extracts of Neurospora crassa
I HAVE recently demonstrated the development of tryptophan synthetase activity by cell-free extracts from conidia of wild-type… 
1958
1958
Restoration of tryptophan synthetase activity in Escherichia coli by suppressor mutations.
1953
1953
Properties of mutants of Neurospora crassa with low pyruvic carboxylase activity.
  • B. Strauss
  • Archives of biochemistry and biophysics
  • 1953
  • Corpus ID: 31334972
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