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tryptophan synthase activity

Known as: L-serine hydro-lyase (adding indoleglycerol-phosphate), L-tryptophan synthetase activity, indoleglycerol phosphate aldolase activity 
Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. [RHEA:10535]
National Institutes of Health

Related topics

Related topics

2 relations
Tryptophan Synthase

Broader (1)

tryptophan biosynthetic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
Prolonged production of tryptophan using immobilized bacteria
Tryptophan production of a genetically modified E. coli strain possessing elevated tryptophan synthetase activity but sensitive… 
1986
1986
Conformational effects of ligand binding on the beta 2 subunit of Escherichia coli tryptophan synthase analyzed with monoclonal antibodies.
Five monoclonal antibodies recognizing five different epitopes of the native beta 2 subunit of Escherichia coli tryptophan… 
1985
1985
Cloning and expression of tryptophan genes from Brevibacterium lactofermentum in Escherichia coli.
1977
1977
Derepression of E. coli trp operon on interfamilial transfer
THE P-group R factor RP4 originally isolated from Pseudomonas aeruginosa can be transferred to many Gram-negative bacteria1–3. In… 
1976
1976
Tryptophan synthase activity, tryptophan and serine contents in pea (Pisum sativum L.) plants during their ontogenesis
Considerable changes in tryptophan synthase aotivity occur during the ontogenesis of pea plants (Pisum sativum L.) in their… 
Highly Cited
1972
Highly Cited
1972
Physiological Studies on Ergot: Further Studies on the Induction of Alkaloid Synthesis by Tryptophan and Its Inhibition by Phosphate
The failure of l-leucine to stimulate ergot alkaloid production in a synthetic medium indicates that the previously observed… 
1969
1969
Effect of gene dosage on tryptophan synthetase activity in Saccharomyces cerevisiae.
A direct relation between gene dosage and amount of the corresponding protein is generally assumed to exist though it has been… 
1960
1960
Mediation of the Genetic Control of Protein Synthesis in Cell-free Extracts of Neurospora crassa
I HAVE recently demonstrated the development of tryptophan synthetase activity by cell-free extracts from conidia of wild-type… 
1958
1958
Restoration of tryptophan synthetase activity in Escherichia coli by suppressor mutations.
1953
1953
Properties of mutants of Neurospora crassa with low pyruvic carboxylase activity.
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