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tropisetron

Known as: (3 alpha-tropanyl)-1H-indole-3-carboxylic acid ester, 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-, indole-3-carboxylic acid tropine ester 
An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

AntiemeticsIndolesSerotonin Antagonists

Narrower (2)

ICS 205-930TROPISETRON HYDROCHLORIDE

Papers overview

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2012
2012
Pretreatment of CAV Combination Chemotherapy with Tropisetron Shows Less Cardio and Neurotoxicity Side Effects in Rats
Tropisetron, a 5-HT3 antagonist receptor, is commonly used for the prevention of emesis following chemotherapy. Lines of evidence… 
2012
2012
Effect of electroacupuncture combined with tropisetron in treating postoperative nausea and vomiting in patients undergoing total hysterectomy
Objective To observe the clinical effect of electroacupuncture (EA) combined with tropisetron on postoperative nausea and… 
2008
2008
Effects of ondansetron alone and in combination with domperidone in the prevention of chemotherapy-induced nausea and vomiting in breast cancer patients
The efficacy and safety of ondansetron, administered alone and in combination with domperidone to prevent chemotherapy-induced… 
2007
2007
Comparison of different methods of administering tropisetron in patient-controlled analgesia in the prevention of postoperative nausea and vomiting
Objective To evaluate the different methods of administering tropisetron in patient-controlled analgesia(PCA) with tramadol in… 
2002
2002
[Dexamethasone enhances the effect of tropisetron and ondansetron against nausea and vomiting against nausea and vomiting after patient-controlled analgesia].
OBJECTIVE To study the enhancement by dexamethasone of the effect of ondansetron and tropiesetron against postoperative nausea… 
2000
2000
Tropisetron zur Prophylaxe von postoperativem Erbrechen bei Kindern
ZusammenfassungFragestellung: Erbrechen und Übelkeit nach Tonsillektomien bei Kindern sind ein häufiges Problem. Aufgrund der… 
2000
2000
Acute rhabdomyolysis after high dose chemotherapy and circulating progenitor cell autografting for breast cancer.
We describe a case of acute rhabdomyolysis developing after high-dose chemotherapy followed by circulating progenitor cell (CPC… 
1999
1999
Prospective randomized comparison of tropisetron with and without dexamethasone against high-dose metoclopramide in prophylaxis of acute and delayed cisplatin-induced nausea and vomiting.
Several studies have confirmed the efficacy of high-dose metoclopramide and, more recently, serotonin antagonists, with and… 
1999
1999
Clozapine's Antipsychotic Effects do not Depend on Blockade of 5-HT3 Receptors
Sixteen known 5-HT3 receptor blockers, including clozapine, fully or partially reverse the inhibitory effect of 1 μM GABA on [35S… 
1998
1998
Tropisetron in the prevention of acute nausea and vomiting in patients treated with high dose epirubicin.
Tropisetron is a novel selective antagonist of the type-3 serotonin (5-HT3) receptor, with proven efficacy in the control of…