FAQ

triphenylethylene

the core chemical structure of a number of related anti-estrogen compounds. The triphenylethylene antiestrogens, which include idoxifene, toremifene… (More)

Topic mentions per year

Topic mentions per year

1947-2016
05101519472015

Related topics

Related topics

2 relations

Broader (2)

Estrogen AntagonistsStilbenes

Related mentions per year

Related mentions per year

1939-2018
19401960198020002020
triphenylethylene
Stilbenes
Estrogen Antagonists

Papers overview

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2004
2004
A new triphenylethylene compound, Fc-1157a
The antitumor effects of a new antiestrogen, Fc-1157a1 have been studied in vitro and in vivo. In vitro the effect of Fc-1157a… (More)
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2000
2000
Selective estrogenic effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact and ovariectomized rats.
FC1271a is a novel triphenylethylene compound with a tissue-selective profile of estrogen agonistic and weak antagonistic effects… (More)
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Highly Cited
1994
Highly Cited
1994
Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.
We have used a series of human estrogen receptor (ER) mutants to evaluate the cell- and promoter-specific transcriptional… (More)
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Highly Cited
1993
Highly Cited
1993
The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat.
Tamoxifen (TAM) is used in the treatment of breast cancer and is being given to healthy women to inhibit breast cancer. The… (More)
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1992
1992
Desmoid tumours treated with triphenylethylenes.
Desmoids are uncommon mesenchymal tumours that occur at single or multiple anatomical sites, occasionally in association with… (More)
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1988
1988
Role of specific interactions between protein kinase C and triphenylethylenes in inhibition of the enzyme.
The tumor promoter receptor protein kinase C (PKC) has been implicated as a key enzyme in cellular growth regulation. It is… (More)
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1987
1987
Triphenylethylene antiestrogen binding sites (TABS) specificity.
The relative binding affinities (RBA) of various compounds for the triphenylethylene antiestrogen binding sites (TABS) were… (More)
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1986
1986
A new triphenylethylene compound, Fc-1157a. II. Antitumor effects.
The antitumor effects of a new antiestrogen, Fc-1157a have been studied in vitro and in vivo. In vitro the effect of Fc-1157a was… (More)
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1986
1986
Triphenylethylenes: a new class of protein kinase C inhibitors.
The Ca2+- and phospholipid-dependent phosphotransferase activity of protein kinase C was inhibited by the triphenylethylene… (More)
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1986
1986
Calmodulin antagonism and growth-inhibiting activity of triphenylethylene antiestrogens in MCF-7 human breast cancer cells.
The triphenylethylene antiestrogen tamoxifen has been shown previously to inhibit both calmodulin and protein kinase C activities… (More)
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